Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | PAM | P19021 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765915 | 0.92 | TSHR (0.45) | TSHRALDH1A1LMNA | |
| SCHEMBL4372085 | 0.91 | ALDH1A1 (0.40) | TSHRALDH1A1 | |
| SCHEMBL273140 | 0.90 | DGKA (0.50) | TSHRALDH1A1LMNADGKAMAPT | |
| SCHEMBL15255073 | 0.89 | DGKA (0.48) | TSHRALDH1A1LMNADGKAMAPT | |
| SCHEMBL3305570 | 0.89 | ALDH1A1 (0.37) | TSHRALDH1A1LMNADGKAMAPT | |
| SCHEMBL10792933 | 0.89 | DGKA (0.48) | TSHRALDH1A1LMNADGKAMAPT | |
| SCHEMBL15392575 | 0.87 | ALDH1A1 (0.40) | TSHRALDH1A1LMNADGKAPTGS1 | |
| SCHEMBL28092776 | 0.83 | FAAH (0.53) | LMNAMAPTPTGS1PRKCA | |
| SCHEMBL5866441 | 0.81 | ALDH1A1 (0.36) | TSHRALDH1A1LMNA | |
| SCHEMBL6836609 | 0.81 | ALDH1A1 (0.36) | TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052265-A1 | A PROTHROMBOGENIC BIOMATERIAL FOR TISSUE REPAIR | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2008-05-08 | — | — | WO | claimed |
| WO-2008052265-A1 | A PROTHROMBOGENIC BIOMATERIAL FOR TISSUE REPAIR | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2008-05-08 | — | — | WO | disclosed |