Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 13/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380548 | 0.91 | TSHR (0.38) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL4369418 | 0.91 | TSHR (0.38) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL4374042 | 0.87 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL4382724 | 0.86 | TSHR (0.39) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL4375460 | 0.86 | TSHR (0.40) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL4376908 | 0.85 | CNR2 (0.39) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL4371357 | 0.84 | KDM4E (0.39) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL4371354 | 0.84 | CNR2 (0.44) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL4382397 | 0.82 | CNR2 (0.42) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL4374299 | 0.82 | CNR2 (0.42) | ALDH1A1KDM4EGAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |