Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 14/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370570 | 0.87 | CNR2 (0.40) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL4372092 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL4374633 | 0.86 | CNR2 (0.41) | CNR2TSHR | |
| SCHEMBL4369418 | 0.85 | TSHR (0.38) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL4380548 | 0.85 | TSHR (0.38) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL4376908 | 0.82 | CNR2 (0.39) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL4374742 | 0.81 | TSHR (0.42) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL4376045 | 0.81 | TSHR (0.42) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL4371354 | 0.80 | CNR2 (0.44) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL4382724 | 0.80 | TSHR (0.39) | ALDH1A1KDM4EGAAGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |