Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 4/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.57 |
| ▸ | ABL1 | P00519 | 10/20 | 0.50 |
| ▸ | BCR | P11274 | 9/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | PRKCA | P17252 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221971 | 0.84 | ABL1 (0.53) | CAMKK2PIK3CGMAPK8ABL1BCR | |
| SCHEMBL22169873 | 0.83 | CAMKK2 (0.74) | CAMKK2PIK3CGMAPK8ABL1BCR | |
| SCHEMBL22169872 | 0.83 | CAMKK2 (0.64) | CAMKK2PIK3CGMAPK8ABL1BCR | |
| SCHEMBL22169842 | 0.82 | CAMKK2 (0.63) | CAMKK2PIK3CGMAPK8ABL1BCR | |
| SCHEMBL29707254 | 0.82 | ABL1 (0.71) | CAMKK2ABL1BCRPDGFRBPDGFRA | |
| SCHEMBL533540 | 0.82 | ABL1 (0.71) | CAMKK2ABL1BCRPDGFRBPDGFRA | |
| SCHEMBL16898354 | 0.80 | ABL1 (0.56) | CAMKK2ABL1BCRPDGFRBPDGFRA | |
| SCHEMBL4373261 | 0.78 | CAMKK2 (0.53) | CAMKK2PIK3CGMAPK8ABL1BCR | |
| SCHEMBL3948017 | 0.78 | ABL1 (0.56) | CAMKK2ABL1BCRPDGFRBPDGFRA | |
| SCHEMBL2984112 | 0.78 | CAMKK2 (0.70) | CAMKK2PIK3CGMAPK8ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109991-A2 | NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) | 2009-09-11 | — | — | WO | claimed |