SCHEMBL4372172

SCHEMBL4372172

COC(CCC=O)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 2/20 0.33
HIF1A Q16665 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9248472 0.82 TSHR (0.42) ALDH1A1TSHRHIF1A
SCHEMBL21855137 0.80 TSHR (0.46) ALDH1A1TSHRHIF1A
SCHEMBL6495615 0.76
SCHEMBL8309538 0.75 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL28886491 0.72 ALDH1A1 (0.38) ALDH1A1TSHRTDP1
SCHEMBL30140506 0.71 ALDH1A1 (0.36) ALDH1A1TSHRTDP1
SCHEMBL10906755 0.71 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL10482216 0.70 TSHR (0.34) ALDH1A1TSHR
SCHEMBL28471510 0.69 ACLY (0.31)
SCHEMBL13438785 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621372-B Ultra-high molecular weight ethylene homopolymers and process for preparing the same 中国石油化工股份有限公司 2024-04-09 CN disclosed
CN-114507310-B Ultra-high molecular weight ethylene copolymer and preparation method thereof 中国石油化工股份有限公司 2024-04-02 CN disclosed
CN-110964140-B In-situ supported non-metallocene catalyst, preparation method and application thereof 中国石油化工股份有限公司 2023-08-04 CN disclosed
CN-110964136-B Composite carrier supported non-metallocene catalyst, preparation method and application thereof 中国石油化工股份有限公司 2023-08-04 CN disclosed
CN-110964132-B Composite carrier segmented in-situ supported non-metallocene catalyst and preparation method thereof 中国石油化工股份有限公司 2023-08-04 CN disclosed
CN-110964137-B Magnesium compound supported non-metallocene catalyst, preparation method and application thereof 中国石油化工股份有限公司 2023-08-01 CN disclosed
CN-110964138-B Magnesium single-carrier segmented in-situ supported non-metallocene catalyst and preparation method thereof 中国石油化工股份有限公司 2023-08-01 CN disclosed
CN-109485762-B Supported non-metallocene catalyst, preparation method and application thereof 中国石油化工股份有限公司 2023-05-26 CN disclosed
CN-110964139-B Magnesium single-carrier in-situ supported non-metallocene catalyst, and preparation method and application thereof 中国石油化工股份有限公司 2023-05-16 CN disclosed
US-7563613-B2 Detoxification and decontamination using nanotechnology therapy UNIVERSITY OF FLORIDA (US) 2009-07-21 US disclosed
EP-1563906-B1 Method of forming a fluid-channel device with covalently bound hard and soft structural components AGILENT TECHNOLOGIES INC (US) 2006-06-21 EP disclosed
US-6977171-B1 Detoxification and decontamination using nanotechnology therapy UNIVERSITY OF FLORIDA (US) 2005-12-20 US disclosed
US-20050274456-A1 Fluid-channel device with covalently bound hard and soft structural components AGILENT TECHNOLOGIES, INC. 2005-12-15 US disclosed
US-20050271734-A1 Detoxification and decontamination using nanotechnology therapy UNIVERSITY OF FLORIDA 2005-12-08 US disclosed
EP-1563906-A1 Method of forming a fluid-channel device with covalently bound hard and soft structural components Agilent Technologies, Inc. (US) 2005-08-17 EP disclosed
WO-2002080885-A1 DETOXIFICATION AND DECONTAMINATION USING NANOTECHNOLOGY THERAPY UNIVERSITY OF FLORIDA (US) 2002-10-17 WO disclosed