Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838378 | 0.80 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL4372172 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL28075576 | 0.71 | — | — | |
| SCHEMBL10839120 | 0.70 | TSHR (0.32) | TSHR | |
| SCHEMBL733382 | 0.69 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL1786827 | 0.69 | ALDH1A1 (0.48) | ALDH1A1TSHRFAAHTRPV1 | |
| SCHEMBL27503123 | 0.69 | — | — | |
| SCHEMBL14778237 | 0.69 | TSHR (0.35) | TSHR | |
| SCHEMBL6495615 | 0.69 | — | — | |
| SCHEMBL14778917 | 0.67 | TSHR (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923569-A1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006711-A1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |