Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.67 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439785 | 0.86 | HAVCR2 (0.68) | HAVCR2PPARAMAPTTHRBKMT2A | |
| SCHEMBL438308 | 0.84 | HAVCR2 (0.57) | HAVCR2MAPTTHRBKMT2AKDM4E | |
| SCHEMBL436903 | 0.84 | KMT2A (0.65) | HAVCR2MAPTTHRBKMT2AKDM4E | |
| SCHEMBL439981 | 0.82 | HAVCR2 (0.55) | HAVCR2MAPTTHRBKMT2AKDM4E | |
| SCHEMBL436942 | 0.80 | HAVCR2 (0.41) | HAVCR2PPARAMAPTTHRBKMT2A | |
| SCHEMBL436716 | 0.80 | HAVCR2 (1.00) | HAVCR2PPARAMAPTKMT2AKDM4E | |
| SCHEMBL2483995 | 0.79 | NPSR1 (0.50) | HAVCR2PPARAMAPTTHRBKMT2A | |
| SCHEMBL442158 | 0.78 | HAVCR2 (0.54) | HAVCR2PPARAMAPTKMT2AKDM4E | |
| SCHEMBL436971 | 0.78 | HAVCR2 (0.61) | HAVCR2PPARAMAPTKMT2AKDM4E | |
| SCHEMBL436434 | 0.77 | HAVCR2 (0.68) | HAVCR2KMT2AKDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |