Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.54 |
| ▸ | GABRP | O00591 | 3/20 | 0.44 |
| ▸ | GABRD | O14764 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.44 |
| ▸ | GABRE | P78334 | 3/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438132 | 0.88 | GABRP (0.49) | HAVCR2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL440068 | 0.88 | HAVCR2 (0.63) | HAVCR2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL440196 | 0.82 | NPC1 (0.52) | KDM4EKMT2AHTTMEN1MAPK1 | |
| SCHEMBL435825 | 0.82 | HAVCR2 (0.50) | HAVCR2KDM4EKMT2ACLCN2PDE4A | |
| SCHEMBL437482 | 0.79 | CYP3A4 (0.35) | HAVCR2KDM4EKMT2AMEN1LMNA | |
| SCHEMBL7502162 | 0.78 | GABRP (0.41) | HAVCR2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL437260 | 0.78 | HAVCR2 (0.67) | HAVCR2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL439833 | 0.76 | HAVCR2 (0.53) | HAVCR2KDM4EKMT2ACLCN2HTT | |
| SCHEMBL436747 | 0.75 | CYP3A4 (0.32) | KDM4EKMT2AMEN1LMNAMAPT | |
| SCHEMBL10482896 | 0.75 | HAVCR2 (0.44) | HAVCR2GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |