Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.68 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437260 | 0.86 | HAVCR2 (0.67) | HAVCR2CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL9654331 | 0.83 | HAVCR2 (0.47) | HAVCR2CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL436716 | 0.81 | HAVCR2 (1.00) | HAVCR2ALDH1A1HTTTSHRMAPT | |
| SCHEMBL437101 | 0.79 | KMT2A (0.65) | HAVCR2ALDH1A1HTTUSP2LMNA | |
| SCHEMBL438820 | 0.78 | HAVCR2 (0.39) | HAVCR2ALDH1A1HTTUSP2LMNA | |
| SCHEMBL440068 | 0.78 | HAVCR2 (0.63) | HAVCR2ALDH1A1LMNATSHRMAPT | |
| SCHEMBL438308 | 0.76 | HAVCR2 (0.57) | HAVCR2ALDH1A1MAPTPOLBNPC1 | |
| SCHEMBL436943 | 0.75 | HAVCR2 (0.56) | HAVCR2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL438978 | 0.75 | HAVCR2 (0.64) | HAVCR2ALDH1A1TSHRMAPTKMT2A | |
| SCHEMBL439981 | 0.74 | HAVCR2 (0.55) | HAVCR2ALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |