Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 19/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966691 | 0.79 | ADRA1A (1.00) | ADRA1AADRA1DADRA2AADRA1B | |
| SCHEMBL31484206 | 0.79 | ADRA1A (1.00) | ADRA1AADRA1DADRA2AADRA1B | |
| SCHEMBL4169374 | 0.74 | ADRA1A (0.55) | ADRA1AADRA1DADRA2AADRA1BCYP19A1 | |
| SCHEMBL9450262 | 0.72 | ADRA1A (0.40) | ADRA1AADRA2A | |
| SCHEMBL14972367 | 0.71 | ADRA1A (0.61) | ADRA1AADRA1DADRA2AADRA1B | |
| SCHEMBL769101 | 0.71 | ADRA1A (1.00) | ADRA1AADRA1DADRA2AADRA1B | |
| SCHEMBL30218164 | 0.70 | ADRA1A (0.52) | ADRA1AADRA1DADRA2AADRA1B | |
| SCHEMBL22284890 | 0.69 | ADRA1A (0.68) | ADRA1AADRA1DADRA2AADRA1B | |
| SCHEMBL23848923 | 0.67 | KDM4E (0.46) | CYP19A1 | |
| SCHEMBL9148202 | 0.66 | CYP19A1 (0.61) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105278-A1 | Selective inhibitors of human corticosteroid syntheses | UNIVERSITAT DES SAARLANDES (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-1768654-A2 | SELECTIVE INHIBITORS OF HUMAN CORTICOSTEROID SYNTHESES | Universität des Saarlandes (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006008316-A2 | SELECTIVE INHIBITORS OF HUMAN CORTICOSTEROID SYNTHESES | Universität des Saarlandes (DE) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105278-A1 | Selective inhibitors of human corticosteroid syntheses | HSD11B1, HSD11B2, CYP11B1 | ADRA1A 287/4885ADRA1D 285/4885ADRA2A 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.