SCHEMBL5806322

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11221012	0.92	ALDH1A1 (0.47)	HPGDALDH1A1KDM4EMAPTADRA2A
	SCHEMBL8171973	0.87	ALDH1A1 (0.47)	HPGDALDH1A1KDM4EMAPTADRA2A
	SCHEMBL9768377	0.86	ADRA2A (0.50)	HPGDALDH1A1KDM4EMAPTADRA2A
	SCHEMBL4780536	0.85	HPGD (0.46)	HPGDALDH1A1KDM4EMAPTADRA2A
	SCHEMBL5196483	0.85	ALDH1A1 (0.46)	HPGDALDH1A1KDM4EMAPTADRA2A
	SCHEMBL28254022	0.85	ALDH1A1 (0.43)	HPGDALDH1A1KDM4EMAPTADRA2A
	SCHEMBL28286605	0.83	TSHR (0.44)	HPGDALDH1A1KDM4EMAPTADRA2A
	SCHEMBL23226950	0.82	HTR2C (0.55)	HPGDALDH1A1KDM4EMAPTADRA2A
	SCHEMBL4796316	0.82	TSHR (0.47)	HPGDALDH1A1KDM4EMAPTTSHR
	SCHEMBL1727026	0.81	ALDH1A1 (0.53)	HPGDALDH1A1KDM4EMAPTADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.