Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 14/20 | 0.60 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687383 | 0.92 | CCR2 (0.62) | CCR2PLA2G4AABCB11 | |
| SCHEMBL16235858 | 0.86 | CCR2 (0.59) | CCR2MCL1ABCB11 | |
| SCHEMBL700700 | 0.85 | CCR2 (0.65) | CCR2ABCB11 | |
| SCHEMBL18962496 | 0.85 | CCR2 (0.56) | CCR2MCL1ABCB11 | |
| SCHEMBL4370468 | 0.84 | ALDH1A1 (0.50) | CCR2PLA2G4AMCL1 | |
| SCHEMBL23301686 | 0.84 | CCR2 (0.55) | CCR2MCL1ABCB11 | |
| SCHEMBL8687188 | 0.84 | KDM4E (0.50) | CCR2 | |
| SCHEMBL23053024 | 0.83 | CCR2 (0.55) | CCR2PLA2G4AMCL1 | |
| SCHEMBL12466305 | 0.83 | ALDH1A1 (0.62) | CCR2PLA2G4AMCL1 | |
| SCHEMBL9040651 | 0.83 | PSEN1 (0.47) | CCR2PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | disclosed |
| US-5852046-A | Benzo-fused heterocyclic compounds having a 5-membered ring processes for their preparation their use as medicaments their use as diagnostic agents and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0639573-A1 | Benzocondensed five membered heterocycles, process of their preparation, their use as drug, as diagnostic means and pharmaceuticals containing it | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-22 | — | — | EP | disclosed |