SCHEMBL4372826

SCHEMBL4372826

O=C(OC(=O)C(O)CO)c1ccccc1C(=O)OC(=O)C(O)CO

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
TSHR P16473 6/20 0.47
CYP3A4 P08684 3/20 0.43
NPC1 O15118 1/20 0.43
TDP1 Q9NUW8 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41
LMNA P02545 1/20 0.40
PRKCA P17252 1/20 0.39
CA2 P00918 1/20 0.38
HSD17B10 Q99714 1/20 0.37
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11715517 0.93 ALDH1A1 (0.51) ALDH1A1TSHRCYP3A4NPC1TDP1
SCHEMBL446203 0.90 TDP1 (0.53) ALDH1A1TSHRNPC1TDP1L3MBTL1
SCHEMBL11335972 0.88 PTPN2 (0.45) ALDH1A1TSHRCYP3A4NPC1TDP1
SCHEMBL15735 0.88 ALDH1A1 (0.54) ALDH1A1TSHRCYP3A4NPC1TDP1
SCHEMBL3390 0.83 ALDH1A1 (0.55) ALDH1A1TSHRNPC1TDP1L3MBTL1
SCHEMBL8922492 0.80 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4TDP1LMNA
SCHEMBL23567080 0.78 PDE4A (0.43) ALDH1A1TSHRCYP3A4NPC1TDP1
SCHEMBL11748379 0.78 ALDH1A1 (0.57) ALDH1A1TSHRCYP3A4TDP1L3MBTL1
Ether SCHEMBL13280294 0.75 LMNA (0.46) ALDH1A1TSHRNPC1TDP1MAPK1
SCHEMBL5198959 0.74 ATM (0.47) ALDH1A1TDP1L3MBTL1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795636-B2 Systems and methods for making thermoplastic products and compositions ENNIS-FLINT, INC. (US) 2023-10-24 US claimed
EP-3307823-B1 DURABLE DEBRIS AND ALKALINE RESISTANT PREFORMED THERMOPLASTIC RUNWAY PAVEMENT MARKING COMPOSITIONS ENNIS FLINT INC (US) 2023-08-16 EP claimed
US-11613655-B2 Systems and methods for making thermoplastic products and compositions ENNIS-FLINT, INC. (US) 2023-03-28 US claimed
US-11279259-B2 Load supporting and insulating apparatuses for rails PRECISION RAIL AND MFG., INC. (US) 2022-03-22 US claimed
EP-3962709-A1 SYSTEMS AND METHODS FOR MAKING THERMOPLASTIC PRODUCTS AND COMPOSITIONS Ennis-Flint, Inc. (US) 2022-03-09 EP claimed
CN-114007838-A Systems and methods for manufacturing thermoplastic products and compositions 恩尼斯-弗林特股份有限公司 2022-02-01 CN claimed
EP-3911486-A1 SYSTEMS AND METHODS FOR MAKING THERMOPLASTIC PRODUCTS AND COMPOSITIONS Ennis-Flint, Inc. (US) 2021-11-24 EP claimed
WO-2020227058-A1 SYSTEMS AND METHODS FOR MAKING THERMOPLASTIC PRODUCTS AND COMPOSITIONS ENNIS-FLINT, INC. (US) 2020-11-12 WO claimed
US-20200347562-A1 Systems and Methods for Making Thermoplastic Products and Compositions ENNIS-FLINT, INC. 2020-11-05 US claimed
WO-2020150337-A1 SYSTEMS AND METHODS FOR MAKING THERMOPLASTIC PRODUCTS AND COMPOSITIONS ENNIS-FLINT, INC. (US) 2020-07-23 WO claimed
US-20200224039-A1 Systems and Methods for Making Thermoplastic Products and Compositions ENNIS-FLINT, INC. 2020-07-16 US claimed
EP-1696014-B1 ELECTROSTATIC PROTECTION, IN PARTICULAR FOR USE IN SPACE CRYOSPACE LAIR LIQUIDE AEROSPATIALE (FR) 2020-05-20 EP claimed
US-20180313046-A1 Durable Debris and Alkaline Resistant Preformed Thermoplastic Runway Pavement Marking Compositions FLINT TRADING INC (US) 2018-11-01 US claimed
US-9951486-B2 Durable debris and alkaline resistant preformed thermoplastic runway pavement marking compositions FLINT TRADING INC. 2018-04-24 US claimed
EP-3307823-A1 DURABLE DEBRIS AND ALKALINE RESISTANT PREFORMED THERMOPLASTIC RUNWAY PAVEMENT MARKING COMPOSITIONS Flint Trading, Inc. (US) 2018-04-18 EP claimed
US-20170211238-A1 Load Supporting and Insulating Apparatuses for Rails PRECISION RAIL AND MFG., INC. (US) 2017-07-27 US claimed
WO-2016200420-A1 DURABLE DEBRIS AND ALKALINE RESISTANT PREFORMED THERMOPLASTIC RUNWAY PAVEMENT MARKING COMPOSITIONS FLINT TRADING, INC. (US) 2016-12-15 WO claimed
US-20160186396-A1 Durable Debris and Alkaline Resistant Preformed Thermoplastic Runway Pavement Marking Compositions FLINT TRADING INC. 2016-06-30 US claimed
CN-1085572-A Improved phenolic resins RYAN BARRY WILLIAM (AU) 1994-04-20 CN claimed
US-4756991-A Pigmented resin particles coated with silicone oil and water soluble polymeric quaternary ammonium compound; nonelectroscopic E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-12 US claimed