SCHEMBL8922492

SCHEMBL8922492

O=C(OC(=O)C(O)CO)c1ccc(C(=O)OC(=O)C(O)CO)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
PRKCA P17252 1/20 0.41
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ESR1 P03372 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
ESR2 Q92731 1/20 0.38
CA14 Q9ULX7 1/20 0.38
ADRB2 P07550 3/20 0.37
ADRB1 P08588 3/20 0.37
ADRB3 P13945 3/20 0.37
LMNA P02545 3/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAOA P21397 1/20 0.37
CYP4F2 P78329 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62519 0.91 LMNA (0.51) ALDH1A1PRKCAKMT2AADRB2ADRB1
SCHEMBL3894587 0.91 PRKCA (0.36) ALDH1A1PRKCAMEN1KMT2AESR1
SCHEMBL6917169 0.91 MAPT (0.49) ALDH1A1PRKCAKMT2AESR1CA12
SCHEMBL3390 0.90 ALDH1A1 (0.55) ALDH1A1PRKCAMEN1KMT2AADRB2
SCHEMBL4529776 0.87 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ALMNACYP3A4
Benzocaine SCHEMBL7263677 0.83 LMNA (0.69) ALDH1A1ESR1CA12CA1CA2
Ether SCHEMBL13280294 0.82 LMNA (0.46) ALDH1A1PRKCAMEN1KMT2AADRB2
SCHEMBL4372826 0.80 ALDH1A1 (0.47) ALDH1A1PRKCACA2LMNACYP3A4
SCHEMBL93977 0.77 OR51E2 (0.50) ALDH1A1LMNATDP1OR51E2
SCHEMBL28435880 0.76 PDE4A (0.46) ALDH1A1PRKCAMEN1KMT2AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9124760-A None JP disclosed
JP-H09124760-A PRODUCTION OF RIGID POLYISOCYANURATE FOAM SANYO CHEM IND LTD 1997-05-13 JP disclosed