Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17202767 | 0.87 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9215585 | 0.85 | MEN1 (0.66) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22938990 | 0.85 | MEN1 (0.84) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL472297 | 0.85 | SMN1; SMN2 (0.57) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL503775 | 0.85 | MEN1 (0.75) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1814072 | 0.85 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1520808 | 0.85 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL11545057 | 0.84 | S100B (0.56) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL10662726 | 0.84 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9617192 | 0.82 | MEN1 (0.79) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291923-A1 | TRIOXANE DIMERS HAVING HIGH ANTICANCER AND LONG-LASTING ANTIMALARIAL ACTIVITIES | JOHNS HOPKINS UNIVERSOTY (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291923-A1 | TRIOXANE DIMERS HAVING HIGH ANTICANCER AND LONG-LASTING ANTIMALARIAL ACTIVITIES | HCCS, XPO5, DHX15 | MEN1 1372/4885KMT2A 2435/4885SMN1; SMN2 2036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.