Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380078 | 0.92 | CHRNB2 (0.33) | PTPN1 | |
| SCHEMBL3742648 | 0.83 | PTPN1 (0.38) | PTPN1HSP90AA1 | |
| SCHEMBL4380083 | 0.79 | TLR8 (0.37) | PTPN1 | |
| SCHEMBL4371511 | 0.78 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL4378608 | 0.78 | PTPN1 (0.36) | PTPN1 | |
| SCHEMBL4376393 | 0.76 | HSP90AA1 (0.35) | HSP90AA1 | |
| SCHEMBL4375859 | 0.75 | PTPN1 (0.42) | PTPN1 | |
| SCHEMBL3735387 | 0.73 | PTPN11 (0.30) | — | |
| SCHEMBL3727477 | 0.71 | PTPN1 (0.38) | PTPN1HSP90AA1 | |
| SCHEMBL4371884 | 0.70 | PTPN1 (0.41) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910359-B1 | PYRIDO [2 , 3-D]PYRIMIDINE-2 , 4-DIAMINE COMPOUNDS AS PTPlB INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-18 | — | — | EP | claimed |
| EP-1910359-B1 | PYRIDO [2 , 3-D]PYRIMIDINE-2 , 4-DIAMINE COMPOUNDS AS PTPlB INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-18 | — | — | EP | disclosed |