Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438920 | 0.89 | ACHE (0.70) | ACHERXFP1SLC2A1ADORA2AADORA1 | |
| SCHEMBL15919363 | 0.83 | ACHE (0.77) | ACHERXFP1SLC2A1ALDH1A1MAPT | |
| SCHEMBL30064742 | 0.83 | RXFP1 (0.61) | ACHERXFP1ALDH1A1MAPTKMT2A | |
| SCHEMBL13774334 | 0.83 | RXFP1 (0.61) | ACHERXFP1ALDH1A1MAPTKMT2A | |
| SCHEMBL4824379 | 0.83 | ACHE (0.71) | ACHERXFP1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL4824929 | 0.82 | EPRS1 (0.68) | ACHERXFP1SLC2A1ALDH1A1MAPT | |
| SCHEMBL4825564 | 0.81 | ACHE (0.51) | ACHERXFP1SLC2A1ADORA2AADORA1 | |
| SCHEMBL9610043 | 0.81 | RXFP1 (0.60) | RXFP1ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL2873300 | 0.80 | ACHE (1.00) | ACHESLC2A1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL3497221 | 0.80 | RXFP1 (0.62) | ACHERXFP1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |