SCHEMBL4373833

SCHEMBL4373833

C=CC(CCCCCCCC)(Cc1ccccc1)C(N)(CC)CC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 1/20 0.38
ARG2 P78540 1/20 0.38
SLC6A2 P23975 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
CSNK1E P49674 1/20 0.37
EBP Q15125 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
DNM1 Q05193 2/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TLR8 Q9NR97 2/20 0.34
TP53 P04637 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
EPHX2 P34913 1/20 0.34
PKM P14618 1/20 0.34
MMP1 P03956 1/20 0.34
MMP9 P14780 1/20 0.34
MMP13 P45452 1/20 0.34
HTT P42858 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4378997 0.92 SLC6A2 (0.43) ARG1ARG2SLC6A2TAAR1CSNK1E
Hydrochloric Acid SCHEMBL11029623 0.90 SLC6A2 (0.42) ARG1ARG2SLC6A2TAAR1CSNK1E
Hydrochloric Acid SCHEMBL5707333 0.90 SLC6A2 (0.42) ARG1ARG2SLC6A2TAAR1CSNK1E
SCHEMBL4379083 0.84 SIGMAR1 (0.36) ARG1ARG2CSNK1EEBPSIGMAR1
SCHEMBL4374768 0.82 MMP1 (0.37) SLC6A2TAAR1CSNK1EEBPSIGMAR1
Ammonia Solution, Strong SCHEMBL27490572 0.81 DNM1 (0.38) SLC6A2TAAR1CSNK1EEBPSIGMAR1
SCHEMBL8945928 0.75 SLC6A2 (0.50) ARG1ARG2SLC6A2TAAR1CSNK1E
SCHEMBL10703166 0.74 CSNK1E (0.38) SLC6A2TAAR1CSNK1EEBPSIGMAR1
SCHEMBL19253988 0.74 SLC6A2 (0.48) SLC6A2TAAR1CSNK1EDNM1MEN1
SCHEMBL11094959 0.74 SLC6A2 (0.48) SLC6A2TAAR1CSNK1EDNM1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090081696-A1 LUMINESCENCE ENHANCER AND USE THEREOF FUJIREBIO INC. (JP) 2009-03-26 US disclosed
EP-2028250-A1 LUMINESCENCE ENHANCER FUJIREBIO INC. (JP) 2009-02-25 EP disclosed