Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 11/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28579033 | 0.82 | CHRM2 (0.37) | ALDH1A1POLBAPEX1RECQLTDP1 | |
| SCHEMBL31065977 | 0.82 | TSHR (0.38) | TSHRPDK2TACR3KCNH2CYP2C19 | |
| SCHEMBL31065923 | 0.69 | P2RX7 (0.51) | PDK2TACR3P2RX7 | |
| SCHEMBL28918494 | 0.68 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL25713579 | 0.67 | MAPK1 (0.38) | TSHRTACR3CYP2C19HTTP2RX7 | |
| SCHEMBL25239634 | 0.65 | P2RX7 (0.51) | PDK2TACR3KCNH2CYP2C19CYP2C9 | |
| SCHEMBL572678 | 0.65 | PDK2 (0.46) | PDK2TACR3P2RX7 | |
| SCHEMBL107990 | 0.65 | P2RX7 (0.57) | PDK2TACR3KCNH2CYP2C19CYP2C9 | |
| SCHEMBL25410612 | 0.63 | DPP4 (0.32) | TSHRHTT | |
| SCHEMBL24097743 | 0.62 | TGFBR1 (0.33) | TSHRPDK2TACR3KCNH2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109364-A1 | NOVEL OXADIAZOLE COMPOUNDS | Abbott Laboratories (US) | 2009-10-21 | — | — | EP | disclosed |
| WO-2008076356-A1 | NOVEL OXADIAZOLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2008-06-26 | — | — | WO | disclosed |