Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.45 |
| ▸ | ITGAV | P06756 | 6/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600972 | 0.85 | ITGAV (0.44) | ITGB3ITGAVGRIN2BOPRD1ENPP2 | |
| SCHEMBL7596629 | 0.85 | ITGAV (0.44) | ITGB3ITGAVGRIN2BOPRD1ENPP2 | |
| SCHEMBL4379967 | 0.84 | ITGB3 (0.65) | ITGB3ITGAV | |
| SCHEMBL4374753 | 0.84 | ITGB3 (0.65) | ITGB3ITGAV | |
| SCHEMBL4045463 | 0.82 | ITGB3 (0.50) | ITGB3ITGAV | |
| SCHEMBL4367915 | 0.82 | ITGAV (0.44) | ITGB3ITGAV | |
| SCHEMBL4368878 | 0.81 | ITGAV (0.47) | ITGB3ITGAV | |
| SCHEMBL4370764 | 0.81 | ITGB3 (0.48) | ITGB3ITGAV | |
| SCHEMBL4376692 | 0.81 | ITGB3 (0.44) | ITGB3ITGAV | |
| SCHEMBL4386638 | 0.80 | ITGB3 (0.43) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047425-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-1047425-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999030709-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |