Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.31 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365892 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HSD17B10LMNASMN1; SMN2FAAH | |
| SCHEMBL675824 | 0.75 | ALDH1A1 (0.42) | ALDH1A1HSD17B10LMNASMN1; SMN2FAAH | |
| SCHEMBL118942 | 0.71 | ALDH1A1 (0.48) | ALDH1A1HSD17B10LMNASMN1; SMN2FAAH | |
| SCHEMBL2397840 | 0.69 | ALDH1A1 (0.47) | ALDH1A1HSD17B10LMNASMN1; SMN2FAAH | |
| SCHEMBL2607864 | 0.69 | — | — | |
| SCHEMBL13756256 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HSD17B10LMNASMN1; SMN2FAAH | |
| SCHEMBL8742043 | 0.67 | ALDH1A1 (0.45) | ALDH1A1HSD17B10LMNASMN1; SMN2FAAH | |
| SCHEMBL1006090 | 0.67 | ALDH1A1 (0.65) | ALDH1A1HSD17B10LMNASMN1; SMN2TSHR | |
| SCHEMBL10621262 | 0.67 | ALDH1A1 (0.50) | ALDH1A1HSD17B10LMNASMN1; SMN2FAAH | |
| SCHEMBL22558178 | 0.67 | ALDH1A1 (0.45) | ALDH1A1HSD17B10LMNASMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117540-A1 | BRIDGED HETEROCYCLES AS HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-09-24 | — | — | WO | disclosed |