SCHEMBL118942

SCHEMBL118942

CC(=O)OCC(=O)OC(=O)COC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.48
HSD17B10 Q99714 3/20 0.48
LMNA P02545 1/20 0.48
TSHR P16473 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.39
CHRM5 P08912 2/20 0.39
CHRM1 P11229 2/20 0.39
CHRM3 P20309 2/20 0.39
PGR P06401 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
HTR1A P08908 1/20 0.39
CHRNB2 P17787 1/20 0.39
TBXA2R P21731 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA7 P36544 1/20 0.39
CHRNA4 P43681 1/20 0.39
CHRNA10 Q9GZZ6 1/20 0.39
CHRNA9 Q9UGM1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2946772 0.92 ALDH1A1 (0.48) ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
SCHEMBL2397840 0.92 ALDH1A1 (0.47) ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
SCHEMBL22558178 0.89 ALDH1A1 (0.45) ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
SCHEMBL8742043 0.89 ALDH1A1 (0.45) ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
SCHEMBL8669971 0.87 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
SCHEMBL27241877 0.87 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
SCHEMBL27556512 0.87 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
SCHEMBL27884437 0.86 ALDH1A1 (0.65) ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
SCHEMBL27599358 0.85 ALDH1A1 (0.41) ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
Ammonia Solution, Strong SCHEMBL27331677 0.85 ALDH1A1 (0.41) ALDH1A1HSD17B10LMNATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132057-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION (US) 2020-06-25 WO claimed
US-20200203711-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-06-25 US claimed
US-11837711-B2 Silicon-based energy storage devices with anhydride containing electrolyte additives ENEVATE CORPORATION (US) 2023-12-05 US disclosed
US-11837711-B2 Silicon-based energy storage devices with anhydride containing electrolyte additives ENEVATE CORPORATION (US) 2023-12-05 US disclosed
CN-110337442-B Novel glucose derivatives as inhibitors of sodium-dependent glucose transporter type 2 东亚ST株式会社 2023-05-12 CN disclosed
US-20210167361-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2021-06-03 US disclosed
US-10957898-B2 Silicon-based energy storage devices with anhydride containing electrolyte additives ENEVATE CORPORATION (US) 2021-03-23 US disclosed
WO-2020242253-A1 NOVEL EMPAGLIFLOZIN DERIVATIVE WHICH IS SGLT-2 INHIBITOR 동아에스티 주식회사 2020-12-03 WO disclosed
WO-2020132057-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION (US) 2020-06-25 WO disclosed
US-20200203711-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-06-25 US disclosed
US-10682419-B2 Prodrugs of peptide epoxy ketone protease inhibitors ONYX THERAPEUTICS, INC. (US) 2020-06-16 US disclosed
US-20160263234-A1 PRODRUGS OF PEPTIDE EPOXY KETONE PROTEASE INHIBITORS ONYX THERAPEUTICS, INC. 2016-09-15 US disclosed
US-9315542-B2 Prodrugs of peptide epoxy ketone protease inhibitors ONYX THERAPEUTICS, INC. (US) 2016-04-19 US disclosed
US-9309283-B2 Prodrugs of peptide epoxy ketone protease inhibitors ONYX THERAPEUTICS, INC. (US) 2016-04-12 US disclosed
EP-2869820-A2 PRODRUGS OF PEPTIDE EPOXY KETONE PROTEASE INHIBITORS Onyx Therapeutics, Inc. (US) 2015-05-13 EP disclosed
US-20140105921-A1 Prodrugs of Peptide Epoxy Ketone Protease Inhibitors ONYX THERAPEUTICS, INC. 2014-04-17 US disclosed
US-20140100154-A1 Prodrugs of Peptide Epoxy Ketone Protease Inhibitors ONYX THERAPEUTICS, INC. (US) 2014-04-10 US disclosed
US-20140100168-A1 Prodrugs of Peptide Epoxy Ketone Protease Inhibitors ONYX THERAPEUTICS, INC. 2014-04-10 US disclosed
WO-2014011695-A2 PRODRUGS OF PEPTIDE EPOXY KETONE PROTEASE INHIBITORS ONYX THERAPEUTICS, INC. (US) 2014-01-16 WO disclosed
US-20120058232-A1 Method for the preparation of diacetyl tartaric acid esters of mono-and di-glycerides LIU GAOFENG (CN) 2012-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140105921-A1 Prodrugs of Peptide Epoxy Ketone Protease Inhibitors PREP, VIP, PEPD ALDH1A1 1285/4885HSD17B10 493/4885LMNA 1138/4885
US-20140100168-A1 Prodrugs of Peptide Epoxy Ketone Protease Inhibitors PREP, VIP, PEPD ALDH1A1 1285/4885HSD17B10 493/4885LMNA 1138/4885
US-20160263234-A1 PRODRUGS OF PEPTIDE EPOXY KETONE PROTEASE INHIBITORS PREP, VIP, PEPD ALDH1A1 1285/4885HSD17B10 493/4885LMNA 1138/4885
US-20140100154-A1 Prodrugs of Peptide Epoxy Ketone Protease Inhibitors PREP, VIP, PEPD ALDH1A1 1285/4885HSD17B10 493/4885LMNA 1138/4885
US-10682419-B2 Prodrugs of peptide epoxy ketone protease inhibitors PREP, VIP, PEPD ALDH1A1 1285/4885HSD17B10 493/4885LMNA 1138/4885
US-20120058232-A1 Method for the preparation of diacetyl tartaric acid esters of mono-and di-glycerides DGAT2, DGAT1, DGKA ALDH1A1 1964/4885HSD17B10 242/4885LMNA 2777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.