Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.39 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675824 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5 | |
| SCHEMBL118942 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5 | |
| SCHEMBL4374433 | 0.81 | ALDH1A1 (0.37) | ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5 | |
| SCHEMBL2397840 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5 | |
| SCHEMBL2607864 | 0.80 | — | — | |
| SCHEMBL6212666 | 0.78 | ALDH1A1 (0.35) | ALDH1A1HSD17B10LMNATSHRFAAH | |
| SCHEMBL6212684 | 0.78 | ALDH1A1 (0.35) | ALDH1A1HSD17B10LMNATSHRFAAH | |
| SCHEMBL11208297 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5 | |
| SCHEMBL22558178 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5 | |
| SCHEMBL3037432 | 0.78 | MGAM (0.48) | ALDH1A1HSD17B10LMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57131735-A | — | — | None | — | — | JP | disclosed |
| US-4831265-A | ANTIFIBROTIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0058057-A1 | Method of producing quinone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1982-08-18 | — | — | EP | disclosed |
| JP-S57131735-A | PREPARATION OF QUINONES | TAKEDA CHEM IND LTD | 1982-08-14 | — | — | JP | disclosed |