SCHEMBL4374736

SCHEMBL4374736

O=S(=O)(c1ccc(Cl)cc1)c1ccc(Oc2ccc(S(=O)(=O)c3ccc(Oc4ccc(S(=O)(=O)c5ccc(Cl)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.73
CYP3A4 P08684 1/20 0.73
MAPK1 P28482 1/20 0.73
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
HTT P42858 3/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PGR P06401 2/20 0.54
KDM4E B2RXH2 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAOA P21397 2/20 0.52
MAOB P27338 2/20 0.52
PKM P14618 1/20 0.52
MMP1 P03956 2/20 0.50
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10708112 1.00 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL14458253 1.00 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL809432 1.00 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL10396881 1.00 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL822784 1.00 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL822642 0.94 ALDH1A1 (0.64) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL2696615 0.90 HTT (0.71) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL9252113 0.90 GAA (0.59) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL14458257 0.90 HTT (0.71) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL822945 0.90 ALDH1A1 (0.59) ALDH1A1CYP3A4MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160149250-A1 ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY, AND SOLID POLYMER FUEL CELL JSR CORPORATION (JP) 2016-05-26 US disclosed
US-8420767-B2 Polyarlene-based polymer, preparation method for the same, and polymer electrolyte membrane for fuel cell using the polymer HYUNDAI MOTOR COMPANY (KR) 2013-04-16 US disclosed
US-20120309857-A1 POLYARYLENE-BASED POLYMER, PREPARATION METHOD FOR THE SAME, AND POLYMER ELECTROLYTE MEMBRANE FOR FUEL CELL USING THE POLYMER HYUNDAI MOTOR COMPANY (KR) 2012-12-06 US disclosed
US-7893303-B2 Polyarylene, process for producing the same, solid polyelectrolyte, and proton-conductive film JSR CORPORATION (JP) 2011-02-22 US disclosed
EP-1245555-B1 Halogenated aromatic compound, polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2009-08-19 EP disclosed
US-20090040690-A1 Electrochemical capacitor JSR CORPORATION (JP) 2009-02-12 US disclosed
US-7396607-B2 Manufacturing process for membrane-electrode assemblies JSR CORPORATION (JP) 2008-07-08 US disclosed
US-7348089-B2 Membrane-electrode assembly for direct methanol type fuel cell and proton conductive membrane JSR CORPORATION (JP) 2008-03-25 US disclosed
US-20080015389-A1 Polyarylene, Process For Producing The Same, Solid Polyelectrolyte, And Proton-Conductive Film JSR CORPORATION (JP) 2008-01-17 US disclosed
US-7163988-B2 Aromatic sulfonic acid ester derivative, polyarylene, polyarylene having sulfonic acid group and process for producing the same, and polymer solid electrolyte and proton-conductive membrane JSR CORPORATION (JP) 2007-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080015389-A1 Polyarylene, Process For Producing The Same, Solid Polyelectrolyte, And Proton-Conductive Film PARG, PUF60, PARN ALDH1A1 3441/4885CYP3A4 3251/4885MAPK1 1651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.