SCHEMBL809432

SCHEMBL809432

O=S(=O)(c1ccc(Cl)cc1)c1ccc(Oc2ccc(S(=O)(=O)c3ccc(Cl)cc3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.73
CYP3A4 P08684 1/20 0.73
MAPK1 P28482 1/20 0.73
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
HTT P42858 3/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PGR P06401 2/20 0.54
KDM4E B2RXH2 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAOA P21397 2/20 0.52
MAOB P27338 2/20 0.52
PKM P14618 1/20 0.52
MMP1 P03956 2/20 0.50
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10708112 1.00 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL14458253 1.00 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL10396881 1.00 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL822784 1.00 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL4374736 1.00 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL822642 0.94 ALDH1A1 (0.64) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL2696615 0.90 HTT (0.71) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL9252113 0.90 GAA (0.59) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL14458257 0.90 HTT (0.71) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL822945 0.90 ALDH1A1 (0.59) ALDH1A1CYP3A4MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3033368-B1 PROCESS FOR MAKING POLYARYLETHERS AND USE IN MEMBRANE PREPARATION FRESENIUS MEDICAL CARE HOLDINGS INC (US) 2023-05-03 EP disclosed
US-20180053956-A1 COMPOSITE POLYMER ELECTROLYTE MEMBRANE, AND CATALYST-COATED MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL USING THE COMPOSITE POLYMER ELECTROLYTE MEMBRANE TORAY INDUSTRIES, INC. (JP) 2018-02-22 US disclosed
US-9748593-B2 Polymer electrolyte composition, and polymer electrolyte membrane, membrane electrode complex and solid polymer-type fuel cell each produced using same TORAY INDUSTRIES, INC. (JP) 2017-08-29 US disclosed
US-9685674-B2 Polymer electrolyte composition, and polymer electrolyte membrane, membrane electrode assembly and solid polymer fuel cell each using same TORAY INDUSTRIES, INC. (JP) 2017-06-20 US disclosed
US-20170125832-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME TORAY INDUSTRIES, INC. (JP) 2017-05-04 US disclosed
US-20170033387-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME CELLCENTRIC GMBH & CO. KG (DE) 2017-02-02 US disclosed
US-20170018793-A1 POLYMER ELECTROLYTE MEMBRANE, CATALYST COATED MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2017-01-19 US disclosed
EP-3033368-A1 PROCESS FOR MAKING POLYARYLETHERS AND USE IN MEMBRANE PREPARATION Fresenius Medical Care Holdings, Inc. (US) 2016-06-22 EP disclosed
US-9353220-B2 Process for making polyarylethers and use in membrane preparation FRESENIUS MEDICAL CARE HOLDINGS, INC. (US) 2016-05-31 US disclosed
US-20150322578-A1 METHOD FOR MANUFACTURING MEMBRANE-ELECTRODE ASSEMBLY, MEMBRANE-ELECTRODE ASSEMBLY, LAMINATE FOR FORMING MEMBRANE-ELECTRODE ASSEMBLY, POLYMER ELECTROLYTE FUEL CELL AND WATER-ELECTROLYSIS DEVICE JSR CORPORATION (JP) 2015-11-12 US disclosed
US-4402879-A Addition products of a di-acetylene-terminated polyimide derivatives and a dienophile having a non-conjugated acetylenic group PLASTICS ENGINEERING COMPANY (US) 1983-09-06 US disclosed
US-4377525-A Addition products of diacetylene-terminated polyimide derivatives and a dienophile having a terminal vinyl group PLASTICS ENGINEERING COMPANY (US) 1983-03-22 US disclosed
US-4377673-A LAMINATION; MOLDING MATERIALS; CROSSLINKING PLASTICS ENGINEERING COMPANY (US) 1983-03-22 US disclosed
US-4331794-A Polymerization products of diimides having terminal diacetylene groups PLASTICS ENGINEERING COMPANY (US) 1982-05-25 US disclosed
US-4331601-A POLYIMIDE MOLDING MATERIALS PLASTICS ENGINEERING COMPANY (US) 1982-05-25 US disclosed
US-4324881-A FROM DIHALOBENZENE COMPOUND AND AMIDE-CONTAINING BISPHENOL, ALKALI METAL CARBONATE BASF AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
US-4200728-A Manufacture of polyethers from bis-(4-hydroxyphenyl)-sulfone and bis-(4-chlorophenyl)-sulfone in N-methylpyrrolidone using an alkali metal carbonate as catalysts BASF AKTIENGESELLSCHAFT (DE) 1980-04-29 US disclosed
US-4200727-A Manufacture of polyethers from bisphenols and dihalides in the absence of solvent and in the presence of alkali metal carbonate BASF AKTIENGESELLSCHAFT (DE) 1980-04-29 US disclosed
US-4169178-A A BISPHENOL OR -DIPHENYL ETHER, SULFIDE, SULFONE, OR KETONE AND A DIHALOBENZENOID COMPOUND AND/OR AN O- OR P-SULFONE- OR KETO-ACTIVATED HALOPHENOL WITH AN ALKALI METAL CARBONATE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-09-25 US disclosed
US-4105636-A BOILING ORGANIC SULPHOXIDE OR SULPHONE SOLVENT CONTAINING MIXTURE OF BISPHENOL AND AN AROMATIC DIHALO COMPOUND OR A HALOPHENOL AND AN ALKALI CARBONATE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-08-08 US disclosed