Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2696615 | 1.00 | HTT (0.71) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL14458252 | 0.95 | HTT (0.65) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL822947 | 0.90 | HTT (0.85) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL12268296 | 0.90 | HTT (0.85) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL2606163 | 0.90 | HTT (0.85) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL4569586 | 0.90 | HTT (0.85) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL822843 | 0.90 | HTT (0.85) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL10084171 | 0.90 | HTT (0.85) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL4374736 | 0.90 | ALDH1A1 (0.73) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL809432 | 0.90 | ALDH1A1 (0.73) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244778-B2 | Filler reinforced polyether imide resin composition and molded article thereof | GENERAL ELECTRIC COMPANY (US) | 2007-07-17 | — | — | US | disclosed |