Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 5/20 | 0.59 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RHOA | P61586 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CDC25A | P30304 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060006 | 0.88 | MAP2K7 (0.45) | CDC25BMAP2K7RAB9ANPC1MAPT | |
| SCHEMBL4382184 | 0.83 | RAB9A (0.45) | CDC25BMAP2K7RAB9ANPC1MAPT | |
| SCHEMBL30193901 | 0.82 | CDC25B (0.71) | CDC25BMAP2K7RAB9ANPC1MAPT | |
| SCHEMBL23831115 | 0.82 | CDC25B (0.71) | CDC25BMAP2K7RAB9ANPC1MAPT | |
| SCHEMBL4058567 | 0.79 | KMT2A (0.41) | RAB9ANPC1MAPTKDM4EMEN1 | |
| SCHEMBL4056980 | 0.77 | NPC1 (0.47) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL29098354 | 0.74 | CDC25B (0.60) | CDC25BMAP2K7RAB9ANPC1MAPT | |
| SCHEMBL13187310 | 0.74 | CDC25B (1.00) | CDC25BMAP2K7RAB9ANPC1MAPT | |
| 3-Phenylamino Benzoic Acid SCHEMBL4345076 | 0.70 | RHOA (0.77) | CDC25BMAP2K7RAB9AMAPTKDM4E | |
| SCHEMBL30633056 | 0.70 | RHOA (0.93) | CDC25BRAB9ANPC1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547713-B2 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2009-06-16 | — | — | US | disclosed |
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | PTGS2, PTGES2, PTGES | CDC25B 359/4885MAP2K7 1803/4885RAB9A 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.