Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24952758 | 0.84 | PDGFRB (0.38) | BRAFPDGFRBPDGFRA | |
| SCHEMBL4377263 | 0.78 | AOC3 (0.36) | MAPTCA12CA1CA9 | |
| SCHEMBL27387671 | 0.76 | CYP11B2 (0.41) | BRAFPDGFRBPDGFRA | |
| SCHEMBL23091812 | 0.74 | ALOX5AP (0.36) | BRAFPDGFRBPDGFRA | |
| SCHEMBL23143271 | 0.74 | MAPT (0.37) | MAPTBRAF | |
| SCHEMBL16043969 | 0.71 | TDP1 (0.50) | TDP1TUBB1CYP3A4MAPTCA12 | |
| SCHEMBL15979195 | 0.70 | — | — | |
| SCHEMBL28783612 | 0.70 | TDP1 (0.33) | TDP1CYP3A4MAPTPDGFRBPDGFRA | |
| SCHEMBL23143268 | 0.69 | LOXL2 (0.46) | PDGFRBPDGFRA | |
| SCHEMBL23143277 | 0.69 | CA1 (0.38) | TDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |