⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4139553 | 1.00 | — | — | |
| SCHEMBL4373913 | 1.00 | — | — | |
| Acetone SCHEMBL10800590 | 0.91 | ADRB2 (0.42) | — | |
| SCHEMBL15509647 | 0.85 | ADRB2 (0.47) | — | |
| SCHEMBL3037240 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL28213102 | 0.81 | LMNA (0.40) | — | |
| SCHEMBL26075439 | 0.80 | ADRB2 (0.42) | — | |
| SCHEMBL15058641 | 0.79 | THRB (0.43) | — | |
| SCHEMBL25554707 | 0.79 | LMNA (0.33) | — | |
| SCHEMBL25554534 | 0.79 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339006-B1 | PROCESS FOR PREPARING S-METOPROLOL AND INTERMEDIATES THEREFOR | Astra Pharmaceutical Production AB (SE) | 1992-07-08 | — | — | EP | claimed |
| US-5034535-A | Multistage reaction with chloroformate ester and isopropylamino-1,2-propanediol for cyclization, sulfonation and etherification | ASTRA PHARMACEUTICAL PRODUCTION AKTIEBOLAG (SE) | 1991-07-23 | — | — | US | claimed |
| EP-0339006-A1 | Process for preparing S-metoprolol and intermediates therefor | Astra Pharmaceutical Production AB (SE) | 1989-10-25 | — | — | EP | claimed |
| JP-2022253-A | — | — | None | — | — | JP | disclosed |
| EP-3998260-B1 | SGC STIMULATORS | CYCLERION THERAPEUTICS INC (US) | 2023-11-01 | — | — | EP | disclosed |
| US-20230303494-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2023-09-28 | — | — | US | disclosed |
| US-20230255945-A1 | FORMULATIONS OF PYRROLOPYRIDINE-ANILINE COMPOUNDS | NFLECTION THERAPEUTICS, INC. | 2023-08-17 | — | — | US | disclosed |
| US-20230255945-A1 | FORMULATIONS OF PYRROLOPYRIDINE-ANILINE COMPOUNDS | NFLECTION THERAPEUTICS, INC. | 2023-08-17 | — | — | US | disclosed |
| CN-109369635-B | Compound or pharmaceutically acceptable salt thereof, application thereof and pharmaceutical composition | 赛克里翁治疗有限公司 | 2023-06-30 | — | — | CN | disclosed |
| EP-4198017-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Academy of Military Medical Sciences (CN) | 2023-06-21 | — | — | EP | disclosed |
| US-20230106002-A1 | sGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. | 2023-04-06 | — | — | US | disclosed |
| WO-2000047212-A1 | QUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | ASTRAZENECA AB (SE) | 2000-08-17 | — | — | WO | disclosed |
| EP-0339006-B1 | PROCESS FOR PREPARING S-METOPROLOL AND INTERMEDIATES THEREFOR | Astra Pharmaceutical Production AB (SE) | 1992-07-08 | — | — | EP | disclosed |
| US-5034535-A | Multistage reaction with chloroformate ester and isopropylamino-1,2-propanediol for cyclization, sulfonation and etherification | ASTRA PHARMACEUTICAL PRODUCTION AKTIEBOLAG (SE) | 1991-07-23 | — | — | US | disclosed |
| US-5034535-A | Multistage reaction with chloroformate ester and isopropylamino-1,2-propanediol for cyclization, sulfonation and etherification | ASTRA PHARMACEUTICAL PRODUCTION AKTIEBOLAG (SE) | 1991-07-23 | — | — | US | disclosed |
| JP-H0222253-A | PRODUCTION OF S-METHOPROLOL | ASTRA PHARMACEUT PROD AB | 1990-01-25 | — | — | JP | disclosed |
| EP-0339006-A1 | Process for preparing S-metoprolol and intermediates therefor | Astra Pharmaceutical Production AB (SE) | 1989-10-25 | — | — | EP | disclosed |
| EP-0339006-A1 | Process for preparing S-metoprolol and intermediates therefor | Astra Pharmaceutical Production AB (SE) | 1989-10-25 | — | — | EP | disclosed |
| US-4031125-A | 3-Sulfonate ester of 2,3-dihydroxypropylamine | MERCK & CO., INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-3962338-A | Novel methods and compounds employed therein | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |