Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.60 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18239754 | 0.81 | HTR6 (0.57) | HTR6PTGDR2PTGDR | |
| SCHEMBL18239786 | 0.79 | HTR6 (0.56) | HTR6PTGDR2PTGDRMAPTPTGS1 | |
| SCHEMBL18222517 | 0.79 | HTR6 (0.56) | HTR6PTGDR2PTGDR | |
| SCHEMBL4374940 | 0.75 | HTR6 (0.49) | HTR6PTGDR2PTGDRMAPTPTGS1 | |
| SCHEMBL5498898 | 0.75 | HTR6 (1.00) | HTR6PTGDR2PTGDR | |
| SCHEMBL3566087 | 0.74 | HTR6 (0.60) | HTR6PTGDR2PTGDR | |
| SCHEMBL18317950 | 0.74 | CA12 (0.43) | MAPT | |
| Oxalic Acid SCHEMBL7448579 | 0.74 | HTR6 (0.71) | HTR6PTGDR2PTGDR | |
| SCHEMBL12628490 | 0.73 | HTR6 (0.56) | HTR6PTGDR2PTGDRMAPTPTGS1 | |
| SCHEMBL1429408 | 0.72 | MEN1 (0.45) | HTR6ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006089-A2 | A2 ADENOSINE RECEPTOR AGONISTS | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-01-08 | — | — | WO | disclosed |