Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 3/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815841 | 0.86 | L3MBTL1 (0.57) | L3MBTL1NR4A2CASP3SENP8SENP7 | |
| SCHEMBL984297 | 0.86 | L3MBTL1 (0.57) | L3MBTL1NR4A2CASP3SENP8SENP7 | |
| SCHEMBL27552883 | 0.85 | L3MBTL1 (0.50) | L3MBTL1NR4A2CASP3SENP8SENP7 | |
| SCHEMBL27840779 | 0.85 | L3MBTL1 (0.56) | L3MBTL1NR4A2CASP3SENP8SENP7 | |
| SCHEMBL140814 | 0.84 | ALDH1A1 (0.57) | L3MBTL1NR4A2CASP3SENP8SENP7 | |
| SCHEMBL11581518 | 0.84 | L3MBTL1 (0.55) | L3MBTL1NR4A2CASP3SENP8SENP7 | |
| SCHEMBL5421974 | 0.83 | L3MBTL1 (0.72) | L3MBTL1NR4A2CASP3SENP8SENP7 | |
| SCHEMBL28837976 | 0.82 | L3MBTL1 (0.54) | L3MBTL1NR4A2CASP3SENP8SENP7 | |
| SCHEMBL2659085 | 0.82 | RAB9A (0.57) | L3MBTL1NR4A2CASP3SENP8SENP7 | |
| SCHEMBL9375354 | 0.82 | L3MBTL1 (0.54) | L3MBTL1NR4A2CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104628639-B | A kind of quinolines containing hepta-fluoroiso-propyl, preparation method and application | 浙江省化工研究院有限公司 | 2018-08-07 | — | — | CN | claimed |
| EP-1997826-A2 | Synthetic ligands for immunoglobulins and pharmaceutical compositions containing them | Tecnogen S.p.A. (IT) | 2008-12-03 | — | — | EP | claimed |
| US-7622612-B2 | Tricyclic derivatives and their use | CHEMTECH RESEARCH INCORPORATION (KR) | 2009-11-24 | — | — | US | disclosed |
| EP-1997826-A2 | Synthetic ligands for immunoglobulins and pharmaceutical compositions containing them | Tecnogen S.p.A. (IT) | 2008-12-03 | — | — | EP | disclosed |
| CN-1304458-C | Process for preparing polycarbonate and apparatus for preparing polycarbonate | GEN ELECTRIC (US) | 2007-03-14 | — | — | CN | disclosed |
| US-20070021427-A1 | Novel tricyclic derivatives and their use | CHEMTECH RESEARCH INCORPORATION (KR) | 2007-01-25 | — | — | US | disclosed |
| CN-1555392-A | Method for preparing polycarbonate and apparatus for preparing polycarbonate | ͨ�õ�����˾ | 2004-12-15 | — | — | CN | disclosed |
| US-4895931-A | ENZYME INHIBITORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| US-4159979-A | P-METHYLBENZYLSULFONYL GROUP FOR AMINO GROUPS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021427-A1 | Novel tricyclic derivatives and their use | NFATC1, IL2, CCL2 | L3MBTL1 4143/4885NR4A2 2682/4885CASP3 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.