Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 9/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009696 | 0.89 | NR4A2 (0.50) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL6991795 | 0.84 | NR4A2 (0.51) | NR4A2CREBBPLMNAMAPTNPSR1 | |
| SCHEMBL15300704 | 0.84 | NR4A2 (0.70) | NR4A2CREBBPF7F3LMNA | |
| SCHEMBL15557355 | 0.83 | KDM4E (0.54) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL1007089 | 0.83 | NR4A2 (0.50) | NR4A2CREBBPF7F3LMNA | |
| SCHEMBL6699986 | 0.83 | NR4A2 (0.72) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL6986880 | 0.83 | NR4A2 (0.72) | GABRA1GABRA3NR4A2CREBBP | |
| SCHEMBL6630345 | 0.82 | NR4A2 (0.49) | GABRG2GABRB3GABRA1GABRA3GABRA2 | |
| SCHEMBL5960313 | 0.82 | HSD17B10 (0.50) | GABRG2GABRB3GABRA1GABRA3GABRA2 | |
| SCHEMBL6687146 | 0.81 | NR4A2 (0.48) | GABRG2GABRB3GABRA1GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094276-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008133753-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2008-11-06 | — | — | WO | disclosed |
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |