Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13743050 | 0.82 | AGTR1 (0.43) | TUBB1DHFRNCOA1NCOA3MEN1 | |
| SCHEMBL4376433 | 0.71 | HPGD (0.44) | TUBB1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL2085154 | 0.71 | KDM4E (0.43) | MEN1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL14432911 | 0.71 | PTGS2 (0.50) | TUBB1DHFRNCOA1NCOA3MEN1 | |
| SCHEMBL4378885 | 0.68 | KDM4E (0.30) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL20676684 | 0.67 | KDM4E (0.46) | DHFRKDM4EMAPK1MAPTTSHR | |
| SCHEMBL21823706 | 0.67 | NCOA1 (0.45) | TUBB1NCOA1NCOA3MEN1KMT2A | |
| SCHEMBL9804771 | 0.66 | CYP3A4 (0.64) | TUBB1DHFRNCOA1NCOA3HSD17B10 | |
| SCHEMBL1731146 | 0.66 | NCOA1 (0.48) | TUBB1NCOA1NCOA3MEN1KMT2A | |
| SCHEMBL18310639 | 0.64 | KMT2A (0.36) | MEN1KMT2AHSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |