Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375741 | 0.84 | GAK (0.38) | SMN1; SMN2SYKCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9833682 | 0.79 | HPGD (0.46) | HPGDSMN1; SMN2SYKMEN1KMT2A | |
| SCHEMBL27863553 | 0.76 | SMN1; SMN2 (0.43) | HPGDSMN1; SMN2SYKMEN1KMT2A | |
| SCHEMBL7850340 | 0.76 | HPGD (0.46) | HPGDSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9834103 | 0.75 | SMN1; SMN2 (0.46) | HPGDSMN1; SMN2SYKMEN1KMT2A | |
| SCHEMBL2035810 | 0.72 | L3MBTL1 (0.53) | SMN1; SMN2MEN1KMT2ATUBB1MAPT | |
| SCHEMBL17506245 | 0.72 | SMN1; SMN2 (0.55) | HPGDSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4375376 | 0.71 | TUBB1 (0.39) | HPGDSMN1; SMN2SYKMEN1KMT2A | |
| SCHEMBL2416876 | 0.71 | HPGD (0.42) | HPGDSMN1; SMN2KMT2AL3MBTL1CA12 | |
| SCHEMBL19612335 | 0.71 | ALDH1A1 (0.50) | SMN1; SMN2SYKMEN1KMT2ATUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |