SCHEMBL437570

SCHEMBL437570

c1ccc(C2(c3cccc4c3sc3ccccc34)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
PARP14 Q460N5 1/20 0.40
GPR3 P46089 1/20 0.39
MAPT P10636 5/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
OPRK1 P41145 1/20 0.39
PRKDC P78527 4/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
RAB9A P51151 2/20 0.33
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
BRD4 O60885 1/20 0.32
PIK3CA P42336 1/20 0.32
MTOR P42345 1/20 0.32
PIK3CG P48736 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL438594 0.94 PARP14 (0.46) ALOX5PARP14GPR3MAPTMEN1
SCHEMBL440562 0.92 PARP14 (0.45) ALOX5PARP14GPR3MAPTMEN1
SCHEMBL22105082 0.90 ALOX5 (0.46) ALOX5PARP14GPR3MAPTMEN1
SCHEMBL16631107 0.88 ALOX5 (0.36) ALOX5PARP14GPR3MAPTMEN1
SCHEMBL12698572 0.86 GPR3 (0.38) ALOX5PARP14GPR3MAPTMEN1
SCHEMBL16631093 0.86 ALOX5 (0.38) ALOX5PARP14GPR3PRKDCTNKS
SCHEMBL328681 0.85 ALOX5 (0.51) ALOX5PARP14GPR3MAPTMEN1
SCHEMBL437557 0.85 ALOX5 (0.51) ALOX5PARP14GPR3MAPTMEN1
SCHEMBL18118731 0.85 ALOX5 (0.36) ALOX5PARP14
SCHEMBL19764669 0.85 GPR3 (0.37) ALOX5PARP14GPR3MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997726-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997726-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9564597-B2 Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-02-07 US disclosed
US-9564597-B2 Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-02-07 US disclosed
US-20160372685-A1 Dibenzothiophene-Containing Materials in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION (US) 2016-12-22 US disclosed
US-20160372685-A1 Dibenzothiophene-Containing Materials in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION (US) 2016-12-22 US disclosed
US-9123903-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-09-01 US disclosed
US-9123903-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-09-01 US disclosed
US-20150243899-A1 Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-08-27 US disclosed
US-20150243899-A1 Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-08-27 US disclosed
US-8580402-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2013-11-12 US disclosed
US-8580402-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2013-11-12 US disclosed
US-20120061714-A1 Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-15 US disclosed
US-20120061714-A1 Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-15 US disclosed
US-20120012829-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2012-01-19 US disclosed
US-20120012829-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2012-01-19 US disclosed
US-8007927-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2011-08-30 US disclosed
US-8007927-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2011-08-30 US disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 US disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES DDT, BPNT1, DBF4 ALOX5 1131/4885PARP14 2217/4885GPR3 4166/4885
US-20150243899-A1 Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound CYP1A1, CYP1B1, DRD1 ALOX5 1299/4885PARP14 3542/4885GPR3 667/4885
US-20120061714-A1 Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound CYP1A1, CYP1B1, DRD1 ALOX5 1299/4885PARP14 3542/4885GPR3 667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.