Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577101 | 0.79 | APEX1 (0.57) | APEX1HTTNPSR1TSHRLMNA | |
| SCHEMBL28227352 | 0.78 | CA1 (0.33) | TSHRKDM4ECA12CA14 | |
| SCHEMBL4373861 | 0.78 | TSHR (0.55) | HTTTSHRLMNAALDH1A1KMT2A | |
| SCHEMBL28217965 | 0.76 | CA1 (0.32) | CA12CA14 | |
| SCHEMBL13715454 | 0.76 | APEX1 (0.48) | APEX1HTTNPSR1TSHRLMNA | |
| SCHEMBL15257418 | 0.75 | APEX1 (0.46) | APEX1HTTNPSR1TSHRLMNA | |
| SCHEMBL778652 | 0.74 | USP2 (0.44) | TSHR | |
| SCHEMBL10306587 | 0.74 | — | — | |
| SCHEMBL28018015 | 0.71 | ALDH1A1 (0.39) | HTTTSHRLMNAALDH1A1KMT2A | |
| SCHEMBL28121803 | 0.71 | APEX1 (0.48) | APEX1HTTNPSR1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103284974-B | Benzene ring nonyl ester double-layer osmotic pump controlled-release tablet and preparation method thereof | WUHAN GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND, PLA (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-103860514-A | Oxybutynin hydrochloride osmotic pump controlled release tablets and preparation method thereof | HEFEI HUAFANG PHARMACEUTICAL SCIENCES & TECHNOLOGY CO LTD | 2014-06-18 | — | — | CN | claimed |
| CN-103284974-A | Phencynonate hydrochloride double-layer osmotic pump controlled release tablet and preparation method thereof | WUHAN GENERAL HOSPITAL OF GUANGZHOU MILITARY | 2013-09-11 | — | — | CN | claimed |
| CN-102552205-A | Potassium citrate controlled-release tablet preparation and preparation method thereof | SHANGHAI INST MATERIA MEDICA | 2012-07-11 | — | — | CN | claimed |
| CN-102488671-A | Lamivudine controlled release tablet preparation and preparation method thereof | HEFEI HUAFANG PHARMACEUTICAL SCIENCES & TECHNOLOGY CO LTD | 2012-06-13 | — | — | CN | claimed |
| CN-102144985-A | Potassium chloride elementary osmotic pump controlled release tablet and preparation method thereof | SHANGHAI INST MATERIA MEDICA | 2011-08-10 | — | — | CN | claimed |
| EP-1592733-B1 | MICROSPHERES | AKZO NOBEL NV (NL) | 2009-07-08 | — | — | EP | claimed |
| CN-100354346-C | Microspheres | AKZO NOBEL NV (NL) | 2007-12-12 | — | — | CN | claimed |
| CN-1805734-A | Biphasic release of glipizide from monocompartment osmotic dosage form | RANBAXY LAB LTD (IN) | 2006-07-19 | — | — | CN | claimed |
| CN-1738853-A | Microspheres | AKZO NOBEL NV (NL) | 2006-02-22 | — | — | CN | claimed |
| EP-1592733-A1 | MICROSPHERES | Akzo Nobel N.V. (NL) | 2005-11-09 | — | — | EP | claimed |
| US-20040249005-A1 | eliminating residual monomers such as (meth)acrylonitrile from thermoplastic expandable microspheres of a thermoplastic polymer shell encapsulating a propellant, by contacting with oxo acids of sulfur such as a bisulfite to form 2-cyano-ethanesulfonic acid for example | AKZO NOBEL N.V. (NL) | 2004-12-09 | — | — | US | claimed |
| WO-2004072160-A1 | MICROSPHERES | AKZO NOBEL N.V. (NL) | 2004-08-26 | — | — | WO | claimed |
| US-20230265121-A9 | CONJUGATED NEUROACTIVE STEROID COMPOSITIONS AND METHODS OF USE | DUKE UNIVERSITY | 2023-08-24 | — | — | US | disclosed |
| CN-103860514-B | A kind of ditropan XL osmotic pump controlled release tablet and preparation method thereof | 合肥华方医药科技有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-103284974-B | Benzene ring nonyl ester double-layer osmotic pump controlled-release tablet and preparation method thereof | WUHAN GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND, PLA (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-1125573-A | The use of asymmmetric membranes in delivery devices | PFIZER (US) | 1996-07-03 | — | — | CN | disclosed |
| EP-0702697-A1 | METHOD OF MAKING AMIDE MODIFIED CARBOXYL-CONTAINING POLYSACCHARIDE AND FATTY AMIDE-MODIFIED POLYSACCHARIDE SO OBTAINABLE | Akzo Nobel N.V. (NL) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994024169-A1 | METHOD OF MAKING AMIDE MODIFIED CARBOXYL-CONTAINING POLYSACCHARIDE AND FATTY AMIDE-MODIFIED POLYSACCHARIDE SO OBTAINABLE | AKZO NOBEL N.V. (NL) | 1994-10-27 | — | — | WO | disclosed |
| CN-1042072-A | Asymmetric membranes for use in delivery assemblies | PFIZER (US) | 1990-05-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265121-A9 | CONJUGATED NEUROACTIVE STEROID COMPOSITIONS AND METHODS OF USE | SHBG, TACR2, GAP43 | APEX1 2942/4885HTT 2692/4885NPSR1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.