Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.45 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28072681 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL31102046 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL4004999 | 0.93 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL7372231 | 0.86 | ALDH1A1 (0.62) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL1964055 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL2826498 | 0.84 | TDP1 (0.56) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL9377747 | 0.84 | TDP1 (0.56) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL613001 | 0.84 | ALDH1A1 (0.53) | ALDH1A1CYP3A4LMNASLC25A1VCAM1 | |
| Hydrochloric Acid SCHEMBL11773238 | 0.82 | ALDH1A1 (0.51) | ALDH1A1CYP3A4LMNASLC25A1VCAM1 | |
| SCHEMBL611920 | 0.82 | ALDH1A1 (0.51) | ALDH1A1CYP3A4LMNASLC25A1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567287-A | Synthesis method of 2, 4-dichloro-5-nitrobenzoic acid | 扬州市荣晶新材料科技有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-105712940-A | Preparation method for Afatinib intermediate 6-nitryl-7-chlorol-4-quinazolinone | 南京师范大学 | 2016-06-29 | — | — | CN | claimed |
| CN-118420528-A | Preparation method of 7-halogeno-6-nitro-1, 4-dihydro-quinoline-4-ketone-3-carbonitrile | 浙江普洛家园药业有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-117586126-A | Synthesis method of 4, 6-dichloro-3-hydroxy-2-nitrobenzoic acid | 扬州市荣晶新材料科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117567287-A | Synthesis method of 2, 4-dichloro-5-nitrobenzoic acid | 扬州市荣晶新材料科技有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117567287-A | Synthesis method of 2, 4-dichloro-5-nitrobenzoic acid | 扬州市荣晶新材料科技有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-105712940-A | Preparation method for Afatinib intermediate 6-nitryl-7-chlorol-4-quinazolinone | 南京师范大学 | 2016-06-29 | — | — | CN | disclosed |
| US-8367824-B2 | Reacting anthranilic acid with formic acid compound in presence of a catalyst and solvent | UBE INDUSTRIES LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| EP-1477481-B1 | PROCESS FOR PRODUCING QUINAZOLIN-4-ONE DERIVATIVE | UBE INDUSTRIES (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-20050080262-A1 | Process for producing quinazolin-4-one derivative | UBE INDUSTRIES, LTD. (JP) | 2005-04-14 | — | — | US | disclosed |
| EP-1477481-A1 | PROCESS FOR PRODUCING QUINAZOLIN-4-ONE DERIVATIVE | Ube Industries, Ltd. (JP) | 2004-11-17 | — | — | EP | disclosed |
| EP-0216028-A2 | Use of anthranilic-acid derivatives as anthelmintic medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080262-A1 | Process for producing quinazolin-4-one derivative | NQO2, SDHA, CYP3A4 | ALDH1A1 477/4885CYP3A4 3/4885ALOX15 3205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.