Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854023 | 0.73 | HTT (0.56) | MEN1HTTKMT2ASRCALDH1A1 | |
| SCHEMBL28306398 | 0.72 | ALDH1A1 (0.43) | MEN1HTTKMT2ACHEK1NEK2 | |
| SCHEMBL12957577 | 0.72 | CHEK1 (0.45) | MEN1KMT2ACHEK1NEK2LIMK1 | |
| SCHEMBL6848277 | 0.71 | MEN1 (0.37) | MEN1HTTKMT2ASRCALDH1A1 | |
| SCHEMBL16838887 | 0.68 | CHEK1 (0.45) | KMT2ACHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL15268120 | 0.67 | CHEK1 (0.48) | MEN1HTTKMT2ACHEK1NEK2 | |
| SCHEMBL29707613 | 0.67 | CHEK1 (0.60) | MEN1KMT2ACHEK1NEK2LIMK1 | |
| SCHEMBL113870 | 0.67 | CHEK1 (0.60) | MEN1KMT2ACHEK1NEK2LIMK1 | |
| Phosphoric Acid SCHEMBL730140 | 0.66 | ALOX15 (0.62) | MEN1KMT2ASRCALDH1A1HSD17B10 | |
| SCHEMBL1838817 | 0.66 | MAPK13 (0.41) | CHEK1NEK2LIMK1DYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009116089-A2 | NOVEL INTERMEDIATES AND METHOD FOR SYNTHESIS OF 4'-[(1,4'-DIMETHYL-2'-PROPYL-[2,6'- BI-1HBENZIMIDAZOL]-L-YL)METHYL]-1,1-BIPHENYL]-2-CARBOXYLIC ACID. | IPCA LABORATORIES LIMITED (IN) | 2009-09-24 | — | — | WO | disclosed |