Phosphoric Acid

Phosphoric Acid

SCHEMBL730140

Nc1ccccc1N.O=P(O)(O)O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.62
CYP3A4 P08684 2/20 0.62
CASP1 P29466 1/20 0.62
CASP7 P55210 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
FDPS P14324 1/20 0.48
TSHR P16473 2/20 0.48
CA2 P00918 2/20 0.46
CA4 P22748 2/20 0.46
CA5A P35218 2/20 0.46
ALDH1A1 P00352 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
GAA P10253 3/20 0.42
HDAC3 O15379 1/20 0.41
MAPK1 P28482 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
MAPT P10636 2/20 0.41
SRC P12931 2/20 0.40
CFTR P13569 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoramidic Acid SCHEMBL10581492 0.91 ALOX15 (0.59) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
Questiomycin B SCHEMBL727121 0.84 ALOX15 (0.75) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
Phosphoric Acid SCHEMBL28420000 0.82 FDPS (0.41) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
Phosphoric Acid SCHEMBL28126181 0.82 TSHR (0.71) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
Questiomycin B SCHEMBL5570900 0.82 ALOX15 (0.71) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
Questiomycin B SCHEMBL28175336 0.82 ALOX15 (0.71) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
O-Tolylamine SCHEMBL6397869 0.82 CYP3A4 (0.68) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL28223590 0.81 CYP3A4 (0.62) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL27769819 0.81 CYP3A4 (0.62) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
Hydrogen Peroxide SCHEMBL5481727 0.79 CYP3A4 (0.83) ALOX15CYP3A4CASP1CASP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343596-B Polymer block copolymer-acrylic ester coating and preparation method thereof 增城市柏雅化工有限公司 2024-05-03 CN claimed
CN-117343596-A Polymer block copolymer-acrylic ester coating and preparation method thereof 增城市柏雅化工有限公司 2024-01-05 CN claimed
CN-109651021-A A kind of full source high-efficiency sustained-release Eco-fertilizer of sweet potato suitable for plains region 山东农大腐植酸高效利用工程技术研发有限公司 2019-04-19 CN claimed
CN-108101614-A Coating controlled-release fertilizer and preparation method thereof 深圳市芭田生态工程股份有限公司 2018-06-01 CN claimed
CN-108083891-A A kind of slow release long-acting compound fertilizer and preparation method thereof 四川汇农新创生物科技有限公司 2018-05-29 CN claimed
CN-104496706-B A kind of ammonium aldehyde dual control composite fertilizer and preparation method thereof 山东史贝美肥料股份有限公司 2018-05-22 CN claimed
CN-106278765-A A kind of organic soil conditioner 张鸿 2017-01-04 CN claimed
CN-105110993-A Controlled-release high-nitrogen liquid fertilizer with effect of improving nitrogen use efficiency and preparation method of controlled-release high-nitrogen liquid fertilizer ANHUI FEITIAN AGRICULTURAL BIOTECHNOLOGY CO LTD 2015-12-02 CN claimed
CN-104496706-A Ammonium-aldehyde dually-controlled compound fertilizer and preparation method thereof SHANDONG SHIBEIMEI FERTILIZER DEV CO LTD 2015-04-08 CN claimed
CN-1247490-C Fertilizer coating composite, its making method and multicomponent coated granular fertilizer CHEN DASHUN (CN) 2006-03-29 CN claimed
CN-1535939-A Fertilizer coating composite, its making method and multicomponent coated granular fertilizer 陈大顺 2004-10-13 CN claimed
CN-117343596-B Polymer block copolymer-acrylic ester coating and preparation method thereof 增城市柏雅化工有限公司 2024-05-03 CN disclosed
CN-117343596-B Polymer block copolymer-acrylic ester coating and preparation method thereof 增城市柏雅化工有限公司 2024-05-03 CN disclosed
CN-117343596-A Polymer block copolymer-acrylic ester coating and preparation method thereof 增城市柏雅化工有限公司 2024-01-05 CN disclosed
CN-117343596-A Polymer block copolymer-acrylic ester coating and preparation method thereof 增城市柏雅化工有限公司 2024-01-05 CN disclosed
EP-1100922-A1 USES OF THE BORRELIACIDAL EPITOPE(S) OF BORRELIA BURGDORFERI OUTER SURFACE PROTEIN C (OSPC) AS VACCINE Gundersen Lutheran Medical Foundation, Inc. (US) 2001-05-23 EP disclosed
US-6210676-B1 Compositions and methods using the borreliacidal epitope(s) of borrelia burgdorferi outer surface protein C (OspC) for the diagnosis and prevention of lyme disease GUNDERSEN LUTHERAN MEDICAL FOUNDATION 2001-04-03 US disclosed
WO-2000006745-A1 USES OF THE BORRELIACIDAL EPITOPE(S) OF BORRELIA BURGDORFERI OUTER SURFACE PROTEIN C (OSPC) AS VACCINE GUNDERSEN LUTHERAN MEDICAL FOUNDATION, INC. (US) 2000-02-10 WO disclosed
US-4681782-A CHAIN EXTENDED POLYETHYLENE, BULLETPROOF DEXTRAN OR POLYVINYL CHLORIDE BIOSTAR MEDICAL PRODUCTS, INC. (US) 1987-07-21 US disclosed
US-4450231-A ABSORPTION OF IMMUNE COMPLEXES BY POLYMER BIOSTAR MEDICAL PRODUCTS, INC. (US) 1984-05-22 US disclosed