SCHEMBL4376673

SCHEMBL4376673

Oc1ccc2c(ccc3c4c(ccc32)C=CC4)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.37
CYP1A2 P05177 1/20 0.34
TYR P14679 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
ESR1 P03372 8/20 0.33
ESR2 Q92731 7/20 0.33
ALOX15 P16050 2/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SHBG P04278 1/20 0.32
PDE2A O00408 1/20 0.31
ABL1 P00519 1/20 0.31
ABCB1 P08183 1/20 0.31
BCR P11274 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12501673 1.00 HNF4A (0.37) HNF4ACYP1A2TYRMEN1LMNA
SCHEMBL22289856 0.84 TYR (0.37) CYP1A2TYRLMNAESR1ESR2
SCHEMBL32677689 0.84 MEN1 (0.36) HNF4ACYP1A2MEN1LMNAPOLB
SCHEMBL29602086 0.80 PDE2A (0.34) KMT2AESR1ESR2PDE2A
SCHEMBL9938343 0.80 PLAU (0.36) MEN1KMT2AALOX15CYP3A4HIF1A
SCHEMBL15903816 0.80 MEN1 (0.32) CYP1A2TYRMEN1LMNAPOLB
SCHEMBL670032 0.78 HNF4A (0.35) HNF4ACYP1A2TYRMEN1LMNA
SCHEMBL12475251 0.77 HPRT1 (0.52) CYP1A2MEN1LMNAKMT2ACYP3A4
SCHEMBL30446008 0.77 HPRT1 (0.52) CYP1A2MEN1LMNAKMT2ACYP3A4
SCHEMBL159626 0.77 HPRT1 (0.52) CYP1A2MEN1LMNAKMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240261393-A1 SARS-COV-2 RNA VACCINE COMPOSITIONS AND METHODS OF USE HDT BIO CORP. 2024-08-08 US claimed
EP-4405372-A1 SARS-COV-2 RNA VACCINE COMPOSITIONS AND METHODS OF USE HDT Bio Corp. (US) 2024-07-31 EP claimed
WO-2023048759-A1 SARS-COV-2 RNA VACCINE COMPOSITIONS AND METHODS OF USE HDT BIO CORP. (US) 2023-03-30 WO claimed
EP-3229809-A1 COMPOUNDS AND METHODS INVOLVING STEROLS Warsaw Orthopedic, Inc. (US) 2017-10-18 EP claimed
WO-2016094421-A1 COMPOUNDS AND METHODS INVOLVING STEROLS WARSAW ORTHOPEDIC, INC. (US) 2016-06-16 WO claimed
WO-2026102175-A1 NMDA RECEPTOR-MODULATORY COMPOUNDS AND METHODS OF USE THEREOF Sage Therapeutics, LLC (US) 2026-05-15 WO disclosed
EP-4713445-A2 RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR (TPA) FRAGMENTS AND USES THEREOF Versiti Blood Research Institute Foundation, Inc. (US) 2026-03-25 EP disclosed
US-20260041754-A1 NANOPARTICLE COMPLEXES FOR ENHANCED SAFETY HDT BIO CORP (US) 2026-02-12 US disclosed
US-20250228930-A1 SARS-COV-2 RNA VACCINE COMPOSITIONS AND METHODS OF USE HDT BIO CORP. 2025-07-17 US disclosed
US-12350329-B2 RNA vaccines against infectious diseases HDT BIO CORP. (US) 2025-07-08 US disclosed
US-20250152736-A1 IMMUNE SYSTEM MODULATORS AND USES THEREOF HDT BIO CORP. 2025-05-15 US disclosed
US-12257299-B2 SARS-CoV-2 RNA vaccine compositions and methods of use HDT BIO CORP. (US) 2025-03-25 US disclosed
WO-2017136549-A1 COMPOUNDS FOR TREATING EYE DISORDERS OR DISEASES YOUHEALTH BIOTECH, LIMITED (KY) 2017-08-10 WO disclosed
WO-2016094421-A1 COMPOUNDS AND METHODS INVOLVING STEROLS WARSAW ORTHOPEDIC, INC. (US) 2016-06-16 WO disclosed
WO-2015184668-A1 ERGOSTEROL COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 正源堂(天津滨海新区)生物科技有限公司 2015-12-10 WO disclosed
WO-2014132213-A1 COMPOUNDS, PROCESSES FOR EXTRACTING THEM FROM KELP, COMPOSITIONS CONTAINING SAID COMPOUNDS AND USE OF SAID COMPOSITIONS LAMICARE HEALTH LTD (GB) 2014-09-04 WO disclosed
EP-2651916-A2 C-17-HETEROARYL STEROIDAL COMPOUNDS AS INHIBITORS OF CYP11B, CYP17, AND/OR CYP21 BioMarin Pharmaceutical Inc. (US) 2013-10-23 EP disclosed
WO-2012083112-A2 CYP11B, CYP17, AND/OR CYP21 INHIBITORS BIOMARIN PHARMACEUTICAL INC. (US) 2012-06-21 WO disclosed
EP-2019620-A2 IMPLANTABLE VOLTAIC CELL Epps, Spencer J.G. (US) 2009-02-04 EP disclosed
WO-2007130694-A2 IMPLANTABLE VOLTAIC CELL EPPS SPENCER J G (US) 2007-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041754-A1 NANOPARTICLE COMPLEXES FOR ENHANCED SAFETY ITGAL, ITGA2B, ITGA2 HNF4A 1940/4885CYP1A2 3698/4885TYR 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.