Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 7/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16227014 | 0.82 | — | — | |
| SCHEMBL12501673 | 0.78 | HNF4A (0.37) | HNF4AMEN1LMNAPOLBKMT2A | |
| SCHEMBL4376673 | 0.78 | HNF4A (0.37) | HNF4AMEN1LMNAPOLBKMT2A | |
| SCHEMBL30526186 | 0.74 | CYP1A2 (0.34) | HNF4AMEN1LMNAPOLBKMT2A | |
| SCHEMBL16226030 | 0.72 | TRPM4 (0.41) | MEN1LMNAPOLBKMT2AALOX15 | |
| SCHEMBL15903816 | 0.71 | MEN1 (0.32) | MEN1LMNAPOLBKMT2ATYR | |
| SCHEMBL1533447 | 0.71 | CYP1A2 (0.57) | HNF4AMEN1LMNAPOLBKMT2A | |
| SCHEMBL1692369 | 0.69 | CYP1A2 (0.55) | HNF4AMEN1LMNAPOLBKMT2A | |
| SCHEMBL29899643 | 0.69 | CYP1A2 (0.55) | HNF4AMEN1LMNAPOLBKMT2A | |
| SCHEMBL30526169 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012022880-A2 | METHOD FOR SYNTHESIZING STEROIDS | UNIVERSITE DE STRASBOURG (FR) | 2012-02-23 | — | — | WO | disclosed |