SCHEMBL437687

SCHEMBL437687

CC(=CCc1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.46
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ARG2 P78540 1/20 0.41
G6PC1 P35575 1/20 0.40
KDM1A O60341 1/20 0.40
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL437686 1.00 MAOB (0.46) MAOBCA1CA2ARG2G6PC1
SCHEMBL437685 1.00 MAOB (0.46) MAOBCA1CA2ARG2G6PC1
SCHEMBL29626995 0.88 LMNA (0.56) LMNA
SCHEMBL6548028 0.88 TP53 (0.46) KDM1A
SCHEMBL6548125 0.88 MEN1 (0.43) LMNA
SCHEMBL6547171 0.88 GPR52 (0.44) MAOB
SCHEMBL5918848 0.87 TRPA1 (0.56) MAOBLMNA
SCHEMBL9588485 0.87 GPR52 (0.43) MAOB
SCHEMBL5918844 0.87 TRPA1 (0.56) MAOBLMNA
SCHEMBL5918838 0.87 TRPA1 (0.56) MAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655307-A1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS Givaudan SA (CH) 2013-10-30 EP claimed
WO-2012085287-A1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS GIVAUDAN SA (CH) 2012-06-28 WO claimed
EP-1132362-B1 HYDROCARBON SOLVENT AND PRESSURE-SENSITIVE COPYING MATERIAL MADE WITH THE SAME NIPPON OIL CORP (JP) 2009-08-26 EP claimed
US-6586362-B1 1-Phenyl-1-(p-isopropylphenyl)ethane made from reaction of styrene and cumene in presence of acid catalyst; dye dissolvers, color developers; odorless NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 2003-07-01 US claimed
EP-1132362-A1 HYDROCARBON SOLVENT AND PRESSURE-SENSITIVE COPYING MATERIAL MADE WITH THE SAME Nippon Petrochemicals Company, Limited (JP) 2001-09-12 EP claimed
US-4347169-A MIXTURE OF A DIARYLALKANE AND AN ARYLINDANE AND-OR 1,3-DIARYLBUTENE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1982-08-31 US claimed
JP-57008215-A None JP disclosed
JP-8053536-A None JP disclosed
JP-9296009-A None JP disclosed
US-20260078233-A1 ENZYMES, MICRO-ORGANISMS AND USES THEREOF, AND A METHOD OF DEGRADING HYDROCARBON CHAINS TEKNOLOGIAN TUTKIMUSKESKUS VTT OY (FI) 2026-03-19 US disclosed
US-20250059221-A1 STAT DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-02-20 US disclosed
CN-118702540-A Production method of styrene rectification polymerization inhibitor 宜兴市中大凯水处理有限公司 2024-09-27 CN disclosed
US-12077555-B2 STAT degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2024-09-03 US disclosed
US-4442027-A Electrical insulating oil composition NIPPON PETROCHEMICALS COMPANY LTD. (JP) 1984-04-10 US disclosed
US-4347169-A MIXTURE OF A DIARYLALKANE AND AN ARYLINDANE AND-OR 1,3-DIARYLBUTENE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1982-08-31 US disclosed
EP-0047998-A1 Electrically insulating oil composition Nippon Petrochemicals Co., Ltd. (JP) 1982-03-24 EP disclosed
JP-S578215-A ODORLESS OR LOW-ORDOR RESIN COMPOSITION HITACHI CHEM CO LTD 1982-01-16 JP disclosed
US-4038309-A PRODUCTION OF 2-HYDROXYNAPHTHALENE-3-CARBOXYLIC ACID BASF AKTIENGESELLSCHAFT (DT) 1977-07-26 US disclosed
US-4032568-A PRODUCTION OF 2-HYDROXYNAPHTHALENE-3-CARBOXYLIC ACID BASF AKTIENGESELLSCHAFT (DT) 1977-06-28 US disclosed
US-3946081-A OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12077555-B2 STAT degraders and uses thereof STAT4, STAT1, STAT3 MAOB 1635/4885CA1 2752/4885CA2 3372/4885
US-20250059221-A1 STAT DEGRADERS AND USES THEREOF STAT4, STAT1, STAT3 MAOB 1635/4885CA1 2752/4885CA2 3372/4885
US-20260078233-A1 ENZYMES, MICRO-ORGANISMS AND USES THEREOF, AND A METHOD OF DEGRADING HYDROCARBON CHAINS PREP, CPSF1, CPSF7 MAOB 1509/4885CA1 3043/4885CA2 3390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.