Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | S100B | P04271 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7807204 | 0.90 | LGMN (0.59) | LGMNMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7513264 | 0.86 | MAPT (0.55) | LGMNMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL31491393 | 0.85 | MAPT (0.71) | LGMNMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4377045 | 0.85 | MAPT (0.71) | LGMNMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL22716931 | 0.83 | LGMN (1.00) | LGMNMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL24507284 | 0.81 | MAPT (0.77) | LGMNMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5825846 | 0.81 | LGMN (0.67) | LGMNMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL923404 | 0.81 | MAPT (0.62) | LGMNMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL520787 | 0.81 | MAPT (0.62) | LGMNMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL27037134 | 0.81 | LGMN (0.67) | LGMNMAPTGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031594-A1 | BENZOXAZOLES AND OXAZOLOPYRIDINES BEING USEFUL AS JANUS KINASES INHIBITORS | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |