Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.35 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | RAD52 | P43351 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1037371 | 0.98 | HTT (0.44) | HTTSMN1; SMN2KDM4ENPC1RAB9A | |
| Iodide SCHEMBL1227463 | 0.98 | HTT (0.44) | HTTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL3742673 | 0.98 | HTT (0.42) | HTTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL9935730 | 0.96 | HTT (0.46) | HTTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL363480 | 0.96 | HTT (0.46) | HTTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL2328683 | 0.96 | HTT (0.46) | HTTSMN1; SMN2KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4377339 | 0.96 | HTT (0.41) | HTTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL1137199 | 0.96 | HTT (0.46) | HTTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL9902243 | 0.96 | HTT (0.46) | HTTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL5086772 | 0.96 | HTT (0.46) | HTTSMN1; SMN2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006126861-A1 | SOLID-STATE ELECTROLYTE COMPOSITION CONTAINING LIQUID CRYSTAL MATERIALS AND DYE-SENSITIZED SOLAR CELLS USING THEREOF | BUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2006-11-30 | — | — | WO | disclosed |