SCHEMBL4377348

SCHEMBL4377348

CCN(CC)c1cccc(NC)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
CYP3A4 P08684 2/20 0.55
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
NOX1 Q9Y5S8 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MAPT P10636 6/20 0.43
TSHR P16473 4/20 0.43
TP53 P04637 3/20 0.43
MAPK1 P28482 3/20 0.43
PKM P14618 2/20 0.43
USP2 O75604 1/20 0.43
MCL1 Q07820 1/20 0.43
HDAC4 P56524 1/20 0.42
MEF2D Q14814 1/20 0.42
TERT O14746 1/20 0.41
NR3C1 P04150 1/20 0.41
KDM4E B2RXH2 3/20 0.40
HPGD P15428 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31657712 1.00 ALDH1A1 (0.55) ALDH1A1CYP3A4MEN1KMT2ANOX1
Sulfuric Acid SCHEMBL9555432 0.90 ALDH1A1 (0.50) ALDH1A1CYP3A4MEN1KMT2ANOX1
SCHEMBL9854054 0.86 ALDH1A1 (0.46) ALDH1A1CYP3A4MEN1KMT2ANOX1
SCHEMBL18976805 0.85 ALDH1A1 (0.39) ALDH1A1CYP3A4MAPTTSHRMAPK1
SCHEMBL10490516 0.84 ALDH1A1 (0.40) ALDH1A1CYP3A4MEN1KMT2ANPC1
SCHEMBL7655949 0.82 ALDH1A1 (0.53) ALDH1A1CYP3A4MEN1KMT2ANOX1
SCHEMBL9799266 0.82 ALDH1A1 (0.53) ALDH1A1CYP3A4MEN1KMT2ANOX1
SCHEMBL11732026 0.81 ALDH1A1 (0.54) ALDH1A1CYP3A4MEN1KMT2ANOX1
SCHEMBL1574035 0.80 ALDH1A1 (0.71) ALDH1A1CYP3A4MEN1KMT2ANPC1
SCHEMBL10808735 0.79 HRH3 (0.40) ALDH1A1CYP3A4MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170349779-A1 ANTI-WEAR AGENT DAICEL CORPORATION (JP) 2017-12-07 US disclosed
EP-3239280-A1 ANTI-WEAR AGENT Daicel Corporation (JP) 2017-11-01 EP disclosed
CN-107109276-A Wear-resisting agent 株式会社大赛璐 2017-08-29 CN disclosed
US-20160186617-A1 SLIDING MEMBER AND METHOD OF MANUFACTURING THE SAME TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2016-06-30 US disclosed
EP-3037491-A1 SLIDING MEMBER AND METHOD OF MANUFACTURING THE SAME Toyota Jidosha Kabushiki Kaisha (JP) 2016-06-29 EP disclosed
CN-103121972-B As the pyrimidine urea derivatives of kinase inhibitor NOVARTIS AG (CH) 2015-07-29 CN disclosed
CN-103121973-A Pyrimidine urea derivatives as kinase inhibitors NOVARTIS AG 2013-05-29 CN disclosed
CN-103121972-A Pyrimidine urea derivatives as kinase inhibitors NOVARTIS AG 2013-05-29 CN disclosed
US-8304469-B2 Highly heat-conductive epoxy resin composition YOKOHAMA RUBBER CO., LTD. (JP) 2012-11-06 US disclosed
US-20090298965-A1 Highly heat-conductive epoxy resin composition YOKOHAMA RUBBER CO., LTD. (JP) 2009-12-03 US disclosed
WO-2003047542-A1 HAIR BLEACHING AND COLOURING COMPOSITION WHICH COMPRISE TRASITION METAL CATALYSTS UNILEVER PLC (GB) 2003-06-12 WO disclosed
US-5051310-A Textured polyurethane molded articles having multiple sheet layers BASF AKTIENGESELLSCHAFT (DE) 1991-09-24 US disclosed
US-4894322-A PYRAZOLTRIAZOLE COMPOUNDS, DEVELOPMENT KONICA CORPORATION (JP) 1990-01-16 US disclosed