Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | S100B | P04271 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31657712 | 0.82 | ALDH1A1 (0.55) | ALDH1A1CYP3A4S100BMEN1KMT2A | |
| SCHEMBL4377348 | 0.82 | ALDH1A1 (0.55) | ALDH1A1CYP3A4S100BMEN1KMT2A | |
| SCHEMBL9799266 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CYP3A4S100BMEN1KMT2A | |
| SCHEMBL11732026 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CYP3A4MEN1KMT2ANOX1 | |
| SCHEMBL1574035 | 0.79 | ALDH1A1 (0.71) | ALDH1A1CYP3A4S100BMEN1KMT2A | |
| SCHEMBL1413227 | 0.78 | ALDH1A1 (0.59) | ALDH1A1CYP3A4S100BMEN1KMT2A | |
| SCHEMBL29931735 | 0.78 | ALDH1A1 (0.59) | ALDH1A1CYP3A4S100BMEN1KMT2A | |
| SCHEMBL11469366 | 0.78 | ALDH1A1 (0.48) | ALDH1A1CYP3A4MEN1KMT2AMAPT | |
| SCHEMBL8942317 | 0.78 | MAPT (0.54) | ALDH1A1CYP3A4MEN1KMT2ANOX1 | |
| SCHEMBL11332567 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP3A4MEN1KMT2ANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407120-B1 | ADMINISTERING PYRIDINYLACETAMIDE OR PHENYLACETAMIDE DERIVATIVE TO TREAT CARDIOVASCULAR, EATING, SEXUAL, BRAIN, NERVOUS SYSTEM, GASTROINTESTINAL, UROGENITAL, PSYCHOLOGICAL, AND RESPIRATORY SYSTEM DISORDERS | PFIZER INC. | 2002-06-18 | — | — | US | disclosed |
| EP-1033366-A2 | Amide derivatives useful as Neuropeptide Y (NPY) antagonists | Pfizer Products Inc. (US) | 2000-09-06 | — | — | EP | disclosed |