SCHEMBL9799266

SCHEMBL9799266

CCNc1cccc(N(CC)CC)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
CYP3A4 P08684 3/20 0.53
HDAC4 P56524 2/20 0.47
MEF2D Q14814 2/20 0.47
MAPT P10636 7/20 0.42
HTT P42858 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
NOX1 Q9Y5S8 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
TP53 P04637 3/20 0.42
MAPK1 P28482 3/20 0.42
TSHR P16473 3/20 0.42
USP2 O75604 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9651245 0.84 ALDH1A1 (0.49) ALDH1A1CYP3A4HDAC4MEF2DMAPT
SCHEMBL4377344 0.83 HDAC4 (0.48) ALDH1A1CYP3A4HDAC4MEF2DMAPT
SCHEMBL4377348 0.82 ALDH1A1 (0.55) ALDH1A1CYP3A4HDAC4MEF2DMAPT
SCHEMBL18338708 0.82 NOS1 (0.48) ALDH1A1CYP3A4HDAC4MEF2DMAPT
SCHEMBL31657712 0.82 ALDH1A1 (0.55) ALDH1A1CYP3A4HDAC4MEF2DMAPT
Diethylaniline SCHEMBL11516531 0.82 MEN1 (0.56) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL9186434 0.82 ALDH1A1 (0.47) ALDH1A1CYP3A4HDAC4MEF2DMAPT
SCHEMBL7655949 0.81 ALDH1A1 (0.53) ALDH1A1CYP3A4HDAC4MEF2DMAPT
SCHEMBL11701480 0.80 HDAC4 (0.47) ALDH1A1CYP3A4HDAC4MEF2DMAPT
SCHEMBL9014365 0.80 HDAC4 (0.53) ALDH1A1CYP3A4HDAC4MEF2DMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1226147-A Method for inproving selectivity in photo-activation and detection of molecular diagnosis agents PHOTOGEN INC (US) 1999-08-18 CN claimed
CN-112384545-B Elastomeric polyurethane foams and process for producing the same 巴斯夫欧洲公司 2023-01-24 CN disclosed
CN-1226147-A Method for inproving selectivity in photo-activation and detection of molecular diagnosis agents PHOTOGEN INC (US) 1999-08-18 CN disclosed
EP-0228190-B1 RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION ETHYL CORPORATION (US) 1991-02-27 EP disclosed
EP-0228190-A2 RIM polyurethanes comprising mixed diamine chain extenders and process and composition for their production ETHYL CORPORATION (US) 1987-07-08 EP disclosed
US-4631298-A REACTION INJECTION MOLDING POLYURETHANES ETHYL CORPORATION (US) 1986-12-23 US disclosed
US-4456541-A Antioxidant diamine ETHYL CORPORATION (US) 1984-06-26 US disclosed