SCHEMBL4377359

SCHEMBL4377359

COC(=O)C1=CC(=O)CC=C1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
TSHR P16473 2/20 0.33
SETD7 Q8WTS6 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
THRB P10828 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
HSD17B10 Q99714 2/20 0.32
POLB P06746 1/20 0.32
BLM P54132 1/20 0.32
MCOLN3 Q8TDD5 1/20 0.32
CA12 O43570 4/20 0.32
CA1 P00915 4/20 0.32
CA2 P00918 4/20 0.32
CA7 P43166 4/20 0.32
CA9 Q16790 4/20 0.32
CA14 Q9ULX7 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10159622 0.79 TSHR (0.34) LMNATSHRALDH1A1HSD17B10CA12
SCHEMBL9335201 0.77 LMNA (0.31) LMNATSHRALDH1A1
SCHEMBL1323323 0.75
SCHEMBL8890220 0.75 SETD7 (0.30) LMNATSHRSETD7ALDH1A1
SCHEMBL7434231 0.74
SCHEMBL23279760 0.71
SCHEMBL48012 0.71 LMNA (0.37) LMNATSHRALDH1A1CHRM2CHRM4
SCHEMBL11087986 0.70 HSP90AA1 (0.37) LMNAALDH1A1TDP1NPSR1
SCHEMBL30507873 0.70 SLC6A3 (0.32) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL16810704 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117420296-A Application of CTAB-Au NCs in antibacterial and/or enzymatic chemiluminescence analysis and substrate solution 上海太阳生物技术有限公司 2024-01-19 CN disclosed
CN-114544947-A Reagent kit for detecting SARS-CoV-2 antigen, method and use thereof 深圳迈瑞生物医疗电子股份有限公司 2022-05-27 CN disclosed
CN-113238046-A Kit for detecting coronavirus antibody and detection method of coronavirus antibody 深圳迈瑞生物医疗电子股份有限公司 2021-08-10 CN disclosed
CN-113219171-A Kit for detecting coronavirus neutralizing antibody and detection method of coronavirus neutralizing antibody 深圳迈瑞生物医疗电子股份有限公司 2021-08-06 CN disclosed
CN-112014577-A Kit for improving detection sensitivity of GPC3 and preparation method thereof 武汉生之源生物科技股份有限公司 2020-12-01 CN disclosed
CN-111781385-A NT-proBNP detection kit and preparation method thereof 武汉生之源生物科技股份有限公司 2020-10-16 CN disclosed
US-20090081696-A1 LUMINESCENCE ENHANCER AND USE THEREOF FUJIREBIO INC. (JP) 2009-03-26 US disclosed
EP-2028250-A1 LUMINESCENCE ENHANCER FUJIREBIO INC. (JP) 2009-02-25 EP disclosed
US-20060199835-A1 Neuroprotective and anti-proliferative compounds AEGERA THERAPEUTICS, INC. (CA) 2006-09-07 US disclosed
WO-2005014584-A9 3-(INDOL-1-YL)-4-(INDOL-3-YL)-PYRROLE-2,5-DIONES,3-(BENZIMIDAZOL-1-YL)-4-(INDOL-3-YL)-PYRROLE-2,5-DIONES, AND 3-(INDOLIN-1-YL)-4-(INDOL-3-YL)-PYRROLE-2,5-DIONES; THEIR PREPARATION AND USE AS MODULATORS OF APOPTOSIS AEGERA THERAPEUTICS INC (CA) 2005-06-23 WO disclosed
US-6287767-B1 FORMING ENZYME COMPLEX BY BINDING ENZYME TO SUBSTANCE; ADDING HYDROPHOBIC FLUORESCENT EMITTER AND 1,2-DIOXITANE COMPOUND; ALLOWING ENZYME TO CLEAVE DIOXITANE COMPOUND; SEGREGATING EMITTER AND OXYANION TO CAUSE FLUORESCENCE TROPIX, INC. 2001-09-11 US disclosed
US-5753436-A Chemiluminescent energy transfer assays TROPIX, INC. (US) 1998-05-19 US disclosed
EP-0450652-B1 Liquid crystalline polyesters and methods for their production MITSUBISHI CHEM CORP (JP) 1997-12-17 EP disclosed
US-5340911-A High impact and tensile strength MITSUBISHI KASEI CORPORATION (JP) 1994-08-23 US disclosed
US-5310859-A Terephthalic acid, hydroxybenzoic acid, ethylene glycol MITSUBISHI KASEI CORPORATION (JP) 1994-05-10 US disclosed
EP-0450652-A2 Liquid crystalline polyesters and methods for their production Mitsubishi Chemical Corporation (JP) 1991-10-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060199835-A1 Neuroprotective and anti-proliferative compounds MKI67, NES, BCL2A1 LMNA 864/4885TSHR 1896/4885SETD7 3543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.