Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020084 | 0.85 | — | — | |
| SCHEMBL23279760 | 0.78 | — | — | |
| SCHEMBL4377359 | 0.75 | LMNA (0.33) | SETD7LMNATSHRALDH1A1 | |
| SCHEMBL10159622 | 0.74 | TSHR (0.34) | LMNATSHRALDH1A1 | |
| SCHEMBL9335201 | 0.71 | LMNA (0.31) | LMNATSHRALDH1A1 | |
| SCHEMBL7890961 | 0.68 | SIGMAR1 (0.40) | SETD7 | |
| SCHEMBL16810704 | 0.65 | — | — | |
| SCHEMBL896075 | 0.63 | CHRM3 (0.39) | LMNATSHRALDH1A1 | |
| SCHEMBL16599541 | 0.62 | CA1 (0.36) | LMNATSHR | |
| SCHEMBL6813512 | 0.61 | CHRM3 (0.31) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602277-A | Substituted benzene derivatives useful as neuraminidase inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996030329-A1 | SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INCORPORATED (US) | 1996-10-03 | — | — | WO | disclosed |