Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | KLF10 | Q13118 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12208533 | 0.89 | ACHE (0.58) | CYP2D6CYP1A2CYP3A4SLC6A2CHRM1 | |
| SCHEMBL27661428 | 0.87 | CYP1A2 (0.52) | CYP2D6CYP1A2CYP3A4SLC6A2CHRM1 | |
| SCHEMBL7429997 | 0.86 | CYP2D6 (0.57) | CYP2D6CYP1A2CYP3A4SLC6A2CHRM1 | |
| SCHEMBL5280197 | 0.86 | CYP2D6 (0.57) | CYP2D6CYP1A2CYP3A4SLC6A2CHRM1 | |
| SCHEMBL4942842 | 0.85 | CYP2D6 (0.56) | CYP2D6CYP1A2CYP3A4SLC6A2CHRM1 | |
| SCHEMBL27661331 | 0.84 | CYP1A2 (0.49) | CYP2D6CYP1A2CYP3A4SLC6A2CHRM1 | |
| SCHEMBL5268496 | 0.82 | SLC6A9 (0.63) | SLC6A4HRH3SLC6A9 | |
| Oxalic Acid SCHEMBL5033726 | 0.81 | CYP1A2 (0.57) | CYP2D6CYP1A2CYP3A4SLC6A2CHRM1 | |
| SCHEMBL25336202 | 0.81 | SLC6A9 (0.41) | CYP2D6SLC6A9ALDH1A1MAPTCYP2C9 | |
| SCHEMBL3894545 | 0.79 | CYP2D6 (0.64) | CYP2D6CYP1A2CYP3A4SLC6A2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141833-A2 | AN IMPROVED PROCESS FOR SYNTHESIZING HIGHLY PURE ATOMOXETINE | IND-SWIFT LABORATORIES LIMITED (IN) | 2009-11-26 | — | — | WO | claimed |
| US-20070270483-A1 | PROCESS FOR THE PREPARATION OF ARYLOXYPROPYLAMINES | DIPHARMA FRANCIS S.R.L. (IT) | 2007-11-22 | — | — | US | claimed |
| EP-1857435-A2 | A process for the preparation of aryloxypropylamines | Dipharma Francis S.r.l. (IT) | 2007-11-21 | — | — | EP | claimed |
| WO-2009141833-A2 | AN IMPROVED PROCESS FOR SYNTHESIZING HIGHLY PURE ATOMOXETINE | IND-SWIFT LABORATORIES LIMITED (IN) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009141833-A2 | AN IMPROVED PROCESS FOR SYNTHESIZING HIGHLY PURE ATOMOXETINE | IND-SWIFT LABORATORIES LIMITED (IN) | 2009-11-26 | — | — | WO | disclosed |
| US-20070270483-A1 | PROCESS FOR THE PREPARATION OF ARYLOXYPROPYLAMINES | DIPHARMA FRANCIS S.R.L. (IT) | 2007-11-22 | — | — | US | disclosed |
| EP-1857435-A2 | A process for the preparation of aryloxypropylamines | Dipharma Francis S.r.l. (IT) | 2007-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270483-A1 | PROCESS FOR THE PREPARATION OF ARYLOXYPROPYLAMINES | NAT1, C1S, PAH | CYP2D6 86/4885CYP1A2 22/4885CYP3A4 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.